Evidence map›Paper›PMID 39542919›Full record

ArticleEuropean journal of applied physiology2025

Effect of experimental knee pain location on gait kinematics.

Alessio Gallina, Paola Adamo, Giorgia Marino, Corrado Cescon, Francesco Bolzoni, Marco Barbero, Federico Temporiti, Roberto Gatti

Abstract read
In one paragraph

Article in European journal of applied physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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  5. Article
  6. The impact of pain from medial meniscus injuries on walking movement patterns.Frontiers in bioengineering and biotechnology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alessio GallinaSchool of Sport, Exercise and Rehabilitation Sciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK. a.gallina@bham.ac.uk.ORCID http://orcid.org/0000-0003-1945-5518
Paola AdamoPhysiotherapy Unit, IRCCS Humanitas Research Hospital, Rozzano, Italy.ORCID http://orcid.org/0000-0002-3003-1153
Giorgia MarinoPhysiotherapy Unit, IRCCS Humanitas Research Hospital, Rozzano, Italy.ORCID http://orcid.org/0009-0000-8599-2739
Corrado CesconRehabilitation Research Laboratory 2rLab, Department of Business Economics, Health and Social Care (DEASS), University of Applied Sciences and Arts of Southern Switzerland (SUPSI), Manno, Switzerland.ORCID http://orcid.org/0000-0002-1632-6684
Francesco BolzoniDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy.ORCID http://orcid.org/0000-0003-3828-2042
Marco BarberoRehabilitation Research Laboratory 2rLab, Department of Business Economics, Health and Social Care (DEASS), University of Applied Sciences and Arts of Southern Switzerland (SUPSI), Manno, Switzerland.ORCID http://orcid.org/0000-0001-8579-0686
Federico TemporitiPhysiotherapy Unit, IRCCS Humanitas Research Hospital, Rozzano, Italy.ORCID http://orcid.org/0000-0003-1771-2365
Roberto GattiPhysiotherapy Unit, IRCCS Humanitas Research Hospital, Rozzano, Italy.ORCID http://orcid.org/0000-0002-4669-1287

Funding

Royal Society IES\R2\212151
6 · The paper itself

Abstract

purposeIn this study, we investigated whether experimental knee pain alters lower limb kinematics and knee arthrokinematics during gait, and if this motor adaptation depends on the spatial characteristics of the painful stimulus.

methodsTwenty-one participants walked on a treadmill for 60-s trials, either without stimulation or while experiencing painful electrical stimulation in the medial, lateral or anterior region of the knee. Perceived pain location was analyzed using pain drawing. Gait spatiotemporal parameters, lower limb kinematics, and dispersion of the knee helical axes on the sagittal plane were quantified for each trial and compared between conditions using ANOVAs with repeated measures or Friedman tests.

resultsPain perception was localized in the area the stimulation was applied to. Compared to walking without pain, participants demonstrated reduced knee extension (1.5 ± 1.5 degrees, p = 0.002) and reduced hip extension (0.8 ± 1.1 degrees, p = 0.037) when pain was induced in the anterior region, but not medially or laterally. Anterior knee pain increased the mean distance of the helical axes during late stance (0.7 [0.3, 1.4], p = 0.010), while medial pain increased both mean distance (0.3 [0.1, 0.5], p = 0.037) and mean angle (1.2 ± 1.4, p = 0.010) during early swing.

conclusionAcute, experimental knee pain alters gait kinematics and increases the dispersion of the helical axis. These adaptations depend on the spatial characteristics of the painful stimulus. These adaptations may reflect an attempt of the central nervous system to protect the painful tissue while searching for a less painful movement strategy.

Indexed as

ArthralgiaGaitKneeKnee JointAdultBiomechanical PhenomenaFemaleHumansMaleYoung AdultArthrokinematicsElectrical stimulationGaitKinematicsKneePain

Identifiers

PMID39542919
PMCPMC11950027

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.