ReviewRevista medica del Instituto Mexicano del Seguro Social2024
[Hyperthermia on colorectal cancer: gold nanoshells-mediated photothermal therapy].
Review in Revista medica del Instituto Mexicano del Seguro Social, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Chemophotothermal Combined Therapy with 5-Fluorouracil and Branched Gold Nanoshell Hyperthermia Induced a Reduction in Tumor Size in a Xenograft Colon Cancer Model.Pharmaceutics · 2025Article
- The Role of Inorganic Nanomaterials in Overcoming Challenges in Colorectal Cancer Diagnosis and Therapy.Pharmaceutics · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Colon cancer or colorectal cancer is one of the most common malignant neoplasms in the world, characterized by uncontrolled cell growth on the colon mucosa. Treatment approaches depend primarily on the characteristics of the tumor´s localization, size, metastasis, and the health status of the patient. Nanomedicine shows itself as a novelty strategy to overcome the limitations of the therapies used in the clinic due to the disregard of the mechanisms associated with multidrug resistance because of the nanometric size of the particles utilized. Gold nanoshells are spheric structures of an approximate size of 30 nm, coated with an ultrathin gold layer that can absorb near-infrared light and convert it to thermal energy to produce hyperthermia on in vivo models of cancer tumors. Nanoparticles-assisted hyperthermia consists of control, direct, and specific heating against the tumor cells by nanoparticle irradiation with an external power source capable of increasing temperature to 39°C - 45°C without damaging surrounding healthy tissue. Compared with other nanomaterials, gold nanoshells show high biocompatibility and low cytotoxicity, which is why adjuvant chemotherapy and hyperthermia on gold nanoshells is a novel and promising approach for the treatment of colorectal cancer.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.