Evidence map›Paper›PMID 39542489›Full record

Trial reportBMJ open2024

Effect of goal-directed mobilisation versus standard care on physical functioning among medical inpatients: the GoMob-in randomised, controlled trial.

Fabian D Liechti, Jeannelle Heinzmann, Nina A Schmutz, Michael L Rossen, Jean-Benoît Rossel, Andreas Limacher, Joachim M Schmidt Leuenberger, Christine Baumgartner, Maria M Wertli, Drahomir Aujesky and 2 more

Registry-linked trialAbstract readEquivalence TrialRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04760392 (Goal-directed Mobilization of Medical Inpatients), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04760392 nacompletednot on this map

Goal-directed Mobilization of Medical Inpatients (GoMob-in) - a Randomized, Controlled Trial

TypeinterventionalSponsorInsel Gruppe AG, University Hospital BernRan2021 to 2023Enrolled160ConditionsImmobility Syndrome, Fall, Delirium, SarcopeniaArmsGoal-directed mobilization
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Fabian D LiechtiDepartment of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland fabian.liechti@insel.ch.ORCID http://orcid.org/0000-0003-1006-6903
Jeannelle HeinzmannDepartment of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Nina A SchmutzDepartment of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Michael L RossenDepartment of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Jean-Benoît RosselCTU Bern, Department of Clinical Research, University of Bern, Bern, Switzerland.
Andreas LimacherCTU Bern, Department of Clinical Research, University of Bern, Bern, Switzerland.
Joachim M Schmidt LeuenbergerDepartment of Physiotherapy, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Christine BaumgartnerDepartment of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0003-2296-9632
Maria M WertliDepartment of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0001-6347-0198
Drahomir AujeskyDepartment of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Martin VerraDepartment of Physiotherapy, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Carole E AubertDepartment of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the effect of goal-directed mobilisation (GDM) on physical functioning in medical inpatients.

designRandomised, controlled, single-centre, parallel, superiority trial with a 3-month follow-up and blinded outcome assessment.

settingGeneral internal medicine wards of a Swiss tertiary acute hospital, September 2021 to April 2023.

participantsAdults with expected hospitalisation of ≥5 days, physiotherapy prescription and ability to follow study procedures.

interventionGDM during hospitalisation, which includes personal goal setting and a short session of patient education through a physiotherapist (experimental group), versus standard care (control group). OUTCOME MEASURES: The primary outcome was the change in physical activity between baseline and day 5 (De Morton Mobility Index (DEMMI)). Secondary outcomes included in-hospital accelerometer-measured mobilisation time; in-hospital falls; delirium; length of stay; change in independence in activities of daily living, concerns of falling and quality of life; falls, readmission and mortality within 3 months.

resultsThe study was completed by 123 of 162 (76%) patients enrolled, with the primary outcome collected at day 5 in 126 (78%) participants. DEMMI Score improved by 8.2 (SD 15.1) points in the control group and 9.4 (SD 14.2) in the intervention group, with a mean difference of 0.3 (adjusted for the stratification factors age and initial DEMMI Score, 95% CI -4.1 to 4.8, p=0.88). We did not observe a statistically significant difference in effects of the interventions on any secondary outcome.

conclusionsThe patient's physical functioning improved during hospitalisation, but the improvement was similar for GDM and standard of care. Improving physical activity during an acute medical hospitalisation remains challenging. Future interventions should target additional barriers that can be implemented without augmenting resources. TRIAL REGISTRATION NUMBER: NCT04760392.

Indexed as

Activities of Daily LivingInpatientsQuality of LifeAccidental FallsAgedAged, 80 and overDeliriumEarly AmbulationExerciseFemaleGoalsHospitalizationHumansLength of StayMaleMiddle AgedAgedHospitalizationHospital to Home TransitionPhysical Therapy ModalitiesQuality in health care

Identifiers

PMID39542489
PMCPMC11575328

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.