Evidence map›Paper›PMID 39542488›Full record

Observational studyBMJ open2024

Primary prevention of cardiovascular diseases among women in a South Asian population: a descriptive study of modifiable risk factors.

Rubina Rauf, Muhammad Nauman Khan, Jawaid Akbar Sial, Nadeem Qamar, Tahir Saghir, Khawar Abbas Kazmi

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06503341 (Assessment and Control of Modifiable Risk Factors for Primary and Secondary Prevention), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06503341 recruitingnot on this map

Assessment and Control of Modifiable Risk Factors for Primary and Secondary Prevention

Typeobservational_patient_registrySponsorNational Institute of Cardiovascular Diseases, PakistanRan2021 to 2041Enrolled10,000ConditionsCardiovascular Morbidity, Cardiovascular Risk Assesment, Primary Prevention CVDArmsCardiovascular risk assesment
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rubina RaufNational Institute of Cardiovascular Diseases, Karachi, Pakistan drrubinarauf@gmail.com.ORCID http://orcid.org/0009-0005-6446-4247
Muhammad Nauman KhanNational Institute of Cardiovascular Diseases, Karachi, Pakistan.
Jawaid Akbar SialNational Institute of Cardiovascular Diseases, Karachi, Pakistan.
Nadeem QamarNational Institute of Cardiovascular Diseases, Karachi, Pakistan.
Tahir SaghirNational Institute of Cardiovascular Diseases, Karachi, Pakistan.
Khawar Abbas KazmiNational Institute of Cardiovascular Diseases, Karachi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was the assessment of modifiable risk factors of cardiovascular diseases (CVD) among women versus men at a newly developed preventive cardiology clinic of a large tertiary care cardiac centre in Pakistan.

designObservational study.

settingTertiary care cardiac hospital in Karachi, Pakistan.

participantsData for this study were obtained retrospectively from a prospectively collected ongoing registry. We have included all female and male individuals who have presented or were referred to our clinic for primary prevention. All the participants had no history of ischaemic heart disease. OUTCOME MEASURE: In this study, we evaluated the CVD risk factors, estimated risk of CVD, and glycaemic and cholesterol control at baseline and at subsequent follow-ups for high-risk patients.

resultsA total of 535 patients, 314 females, were included with a mean age of 48.3±12.5 years. At baseline, 57.9% (128) of men versus 73.2% (230) of women (p<0.001) were known cases of hypertension (HTN); 18.1% (40) vs 26.8% (84) (p=0.019) were diabetic; 40.5% (89) vs 9.2% (29) (p<0.001) were tobacco users; 26.0% (56) vs 3.2% (10) (p<0.001) were smokers; and 26.9% (57) vs 50.5% (153) had BMI ≥30 kg/m

conclusionsThere is a high prevalence of modifiable risk factors for atherosclerotic CVD such as HTN, diabetes and obesity in women as compared with men, but interestingly, ASCVD risk score at the baseline as well as at the follow-up is high in men versus women. Some other non-modifiable risk factors like age, gender and blood lipid profile may also contribute to this difference between the high prevalence of risk factors and low ASCVD risk score in women. With appropriate follow-up and proper counselling, the looming CVD can be better prevented in this population. A dedicated preventive cardiology clinic for the identification of high-risk women and systematic follow-up is needed to predict their actual CVD risk.

trial registrationNCT06503341.

Indexed as

Cardiovascular DiseasesPrimary PreventionAdultCholesterolDiabetes MellitusFemaleHeart Disease Risk FactorsHumansHypertensionMaleMiddle AgedPakistanRetrospective StudiesRisk FactorsSex FactorsCholesterolAdult cardiologyCardiovascular DiseasePrevalencePreventive Health ServicesPreventive MedicineRisk Factors

Identifiers

PMID39542488
PMCPMC11575297

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.