ArticleThe lancet. Diabetes & endocrinology2024
Trends in the incidence of young-adult-onset diabetes by diabetes type: a multi-national population-based study from an international diabetes consortium.
Article in The lancet. Diabetes & endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Precision Medicine to Redefine Insulin Secretion and Monogenic Diabetes (PRISM): A Randomized Controlled Trial in Chinese Patients With Young-Onset Diabetes.Diabetes care · 2026Trial
- Clinical obesity in Asian people: bridging the gap between adiposity and disease.Nature reviews. Endocrinology · 2026Review
- Trends in type 2 diabetes incidence and BMI at diagnosis by age, sex, and ethnicity, 2011-2024: a population-based analysis of the English National Diabetes Audit.The Lancet regional health. Europe · 2026Article
- Prevalence, incidence, mortality, and years of life lost to diabetes from 1996 to 2024 in Denmark.BMJ open diabetes research & care · 2026Article
- Cardiovascular disease risk factors in young people with diabetes mellitus.Cardiovascular diabetology. Endocrinology reports · 2026Article
- The Genetic Landscape of Diabetes Mellitus: Lessons from Monogenic and Polygenic Forms.Life (Basel, Switzerland) · 2026Review
- Exploring the interpretive processes of symptom perception among diabetes patients in eastern region of Ghana.Dialogues in health · 2025Article
- Increasing incidence of early-onset type 2 diabetes in Sweden 2006-2021.European journal of public health · 2025Article
- Relationship between skeletal muscle mass and glycemic parameters in individuals with young-onset type 2 diabetes mellitus.Irish journal of medical science · 2025Article
- Article
- Site-specific adaptive nanovesicles for oral insulin delivery.Science advances · 2025Article
- Young-onset type 2 diabetes-Epidemiology, pathophysiology, and management.Journal of diabetes investigation · 2025Review
- Proteomic signatures of type 2 diabetes predict the incidence of coronary heart disease.Cardiovascular diabetology · 2025Article
- Ahmedabad declaration: A framework to combat growing epidemic of young-onset type 2 diabetes in Asia.Diabetes & metabolic syndrome · 2025Review
- Clinical Characteristics and Development of Complications Differ Between Adult-Onset and Child-Adolescent-Onset Type 1 Diabetes: A Report From a Tertiary Medical Center in Türkiye.Journal of diabetes research · 2025Observational
Corrections and comments
- Commented on by
Authors and funding
20 authors.
Funding
Abstract
backgroundPopulation-based incidence data on young-adult-onset type 1 diabetes and type 2 diabetes are limited. We aimed to examine secular trends in the incidence of diagnosed type 1 diabetes and type 2 diabetes with an age of onset between 15 and 39 years.
methodsIn this multicountry aggregate data analysis, we assembled eight administrative datasets from high-income jurisdictions and countries (Australia, Denmark, Finland, Hungary, Japan, Scotland, South Korea, and Spain [Catalonia]) that had appropriate data available from an international diabetes consortium (GLOBODIAB) describing incidence by diabetes type among people aged 15-39 years from 2000 to 2020. We modelled type 1 diabetes and type 2 diabetes incidence rates using Poisson regression including age and calendar time by sex.
findingsDuring the years 2000-20, there were 349 591 incident diabetes (both types) cases from 346 million person-years of follow-up among people aged 15-39 years. Over time, there was no statistically significant change in the incidence of type 1 diabetes in Hungary and Japan. The incidence of type 1 diabetes significantly increased in Australia, Denmark, Finland, Scotland, South Korea, and Spain, with annual changes ranging from 0·5% to 6·0%. The incidence of type 2 diabetes significantly increased in four of eight jurisdictions (Denmark, Finland, Japan, and South Korea), with annual increases from 2·0% to 8·5%. The magnitude of increase in incidence of type 2 diabetes was greater in Asian than non-Asian jurisdictions. There was no statistically significant change in type 2 diabetes incidence in Australia and Hungary. The incidence of type 2 diabetes significantly decreased in Scotland and Spain, with annual changes of -0·7% and -1·5%, respectively.
interpretationThere is variability in the trajectory of the incidence of young-adult-onset type 2 diabetes among high-income countries or jurisdictions, with a greater evidence of increase in Asian than non-Asian countries. Evolving trends in the incidence of type 1 and type 2 diabetes in young adults call for the ongoing surveillance of diabetes incidence and a greater research focus on this population.
fundingUS Centers for Disease Control and Prevention, Diabetes Australia Research Programme, and Victoria State Government Operational Infrastructure Support Programme.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.