Evidence map›Paper›PMID 39541969›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2024

R-loops facilitate AAV-mediated nuclease-free gene targeting.

Bryan Hu, Roland W Herzog, Dongsheng Duan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bryan HuDepartment of Molecular Microbiology and Immunology, University of Missouri, Columbia, MO 65212, USA.
Roland W HerzogDepartment of Pediatrics, Herman B. Wells Center for Pediatric Research, Indiana University, Indianapolis, IN 46202, USA.
Dongsheng DuanDepartment of Molecular Microbiology and Immunology, University of Missouri, Columbia, MO 65212, USA; Department of Neurology, School of Medicine, Department of Biomedical Sciences, College of Veterinary Medicine, Department of Chemical and Biomedical Engineering, College of Engineering, University of Missouri, Columbia, MO 65212, USA. Electronic address: duand@missouri.edu.

Funding

Mechanism of immune response to muscle-directed AAV gene transferR01AI177600 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI Dongsheng Duan, Roland W. Herzog · 2023 to 2026
$3.1M
CRISPR editing therapy for Duchenne muscular dystrophyR01NS131416 · NINDS · UNIVERSITY OF MISSOURI-COLUMBIA · PI Dongsheng Duan · 2023 to 2026
$2.2M
NIAID NIH HHS R01 AI177600NINDS NIH HHS R01 NS131416
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39541969
PMCPMC11638859

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.