Evidence map›Paper›PMID 39541521›Full record

ArticleExperimental and clinical psychopharmacology2025

Evaluating the human abuse potential of concurrent use of electronic cigarettes and low nicotine cigarettes among adults who smoke.

Jason D Robinson, Yong Cui, George Kypriotakis, Jeffrey M Engelmann, Maher Karam-Hage, Jennifer A Minnix, Charles E Green, Sanjay Shete, Dorothy K Hatsukami, Eric C Donny and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental and clinical psychopharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Standardized research electronic cigarette acceptability among adult men and women who smoke combustible cigarettes.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025
    Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jason D RobinsonDepartment of Behavioral Science, University of Texas MD Anderson Cancer Center.ORCID 0000-0002-1588-9637
Yong CuiDepartment of Behavioral Science, University of Texas MD Anderson Cancer Center.
George KypriotakisDepartment of Behavioral Science, University of Texas MD Anderson Cancer Center.
Jeffrey M EngelmannRogers Behavioral Health.
Maher Karam-HageDepartment of Behavioral Science, University of Texas MD Anderson Cancer Center.
Jennifer A MinnixDepartment of Behavioral Science, University of Texas MD Anderson Cancer Center.
Charles E GreenDepartment of Pediatrics, University of Texas Health Science Center at Houston.
Sanjay SheteDepartments of Biostatistics and Epidemiology, University of Texas MD Anderson Cancer Center.
Dorothy K HatsukamiMasonic Cancer Center, University of Minnesota.
Eric C DonnyDepartment of Translational Neuroscience, Wake Forest University School of Medicine.
Sharon E MurphyMasonic Cancer Center, University of Minnesota.
Stephen S HechtMasonic Cancer Center, University of Minnesota.
Thomas EissenbergDepartment of Psychology, Center for the Study of Tobacco Products, Virginia Commonwealth University.
David W WetterCenter for Health Outcomes and Population Equity, Huntsman Cancer Institute, University of Utah.
Paul M CinciripiniDepartment of Behavioral Science, University of Texas MD Anderson Cancer Center.

Funding

TRANSLATIONAL AND ANALYTICAL CHEMISTRY COREP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI PETER W PISTERS · 1985 to 2026
$279.3M
CTSA UM1 Program at University of UtahUM1TR004409 · NCATS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI RACHEL HESS, Jennifer Juhl Majersik · 2023 to 2026
$21.9M
Evaluating Concomitant Use of Very Low Nicotine Content Cigarettes and E-cigarettes Among Daily and Non-Daily Smokers on Abuse LiabilityR01DA042526 · NIDA · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI CINCIRIPINI, PAUL MICHAEL, ROBINSON, JASON D · 2016 to 2019
$3.1M
National Institutes of Health; National Institute on Drug AbuseNCATS NIH HHS UM1 TR004409NCI NIH HHS P30 CA016672NIDA NIH HHS R01 DA042526
6 · The paper itself

Abstract

The U.S. Food and Drug Administration has stated its intention to reduce the nicotine content of combustible cigarettes to render them less addictive. This study evaluated the impact of providing adults who smoke with both very low nicotine content cigarettes (VLNCCs) and electronic cigarettes (ECs) of varying nicotine content on measures of human abuse potential. Participants (

Indexed as

Cigarette SmokingElectronic Nicotine Delivery SystemsNicotineTobacco ProductsTobacco Use DisorderVapingAdultFemaleHumansMaleMiddle AgedYoung AdultNicotine

Identifiers

PMID39541521
PMCPMC11932771

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.