Evidence map›Paper›PMID 39541276›Full record

ArticlePLOS digital health2024

Leveraging explainable artificial intelligence for early prediction of bloodstream infections using historical electronic health records.

Rajeev Bopche, Lise Tuset Gustad, Jan Egil Afset, Birgitta Ehrnström, Jan Kristian Damås, Øystein Nytrø

Abstract read
In one paragraph

Article in PLOS digital health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. From Narrative to Navigation-A Translational Roadmap for AI-enabled Early Sepsis Prediction: Comment on Shanmugam et al.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rajeev BopcheDepartment of Computer Science, Norwegian University of Science and Technology, Trondheim, Norway.ORCID https://orcid.org/0000-0003-4835-9488
Lise Tuset GustadFaculty of Nursing and Health Sciences, Nord University, Levanger, Norway.ORCID https://orcid.org/0000-0003-2709-3991
Jan Egil AfsetDepartment of Medical Microbiology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
Birgitta EhrnströmDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.ORCID https://orcid.org/0000-0003-4233-5725
Jan Kristian DamåsDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
Øystein NytrøDepartment of Computer Science, Norwegian University of Science and Technology, Trondheim, Norway.ORCID https://orcid.org/0000-0002-8163-2362

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bloodstream infections (BSIs) are a severe public health threat due to their rapid progression into critical conditions like sepsis. This study presents a novel eXplainable Artificial Intelligence (XAI) framework to predict BSIs using historical electronic health records (EHRs). Leveraging a dataset from St. Olavs Hospital in Trondheim, Norway, encompassing 35,591 patients, the framework integrates demographic, laboratory, and comprehensive medical history data to classify patients into high-risk and low-risk BSI groups. By avoiding reliance on real-time clinical data, our model allows for enhanced scalability across various healthcare settings, including resource-limited environments. The XAI framework significantly outperformed traditional models, particularly with tree-based algorithms, demonstrating superior specificity and sensitivity in BSI prediction. This approach promises to optimize resource allocation and potentially reduce healthcare costs while providing interpretability for clinical decision-making, making it a valuable tool in hospital systems for early intervention and improved patient outcomes.

Identifiers

PMID39541276
PMCPMC11563427

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.