Evidence map›Paper›PMID 39541153›Full record

ArticleeLife2024

Chemokine expression profile of an innate granuloma.

Megan E Amason, Cole J Beatty, Carissa K Harvest, Daniel R Saban, Edward A Miao

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Megan E AmasonDepartment of Integrative Immunobiology, Duke University School of Medicine, Durham, United States.ORCID https://orcid.org/0009-0000-2834-5834
Cole J BeattyDepartment of Integrative Immunobiology, Duke University School of Medicine, Durham, United States.
Carissa K HarvestDepartment of Integrative Immunobiology, Duke University School of Medicine, Durham, United States.
Daniel R SabanDepartment of Integrative Immunobiology, Duke University School of Medicine, Durham, United States.
Edward A MiaoDepartment of Integrative Immunobiology, Duke University School of Medicine, Durham, United States.ORCID https://orcid.org/0000-0001-7295-3490

Funding

VISION RESEARCHP30EY005722 · NEI · DUKE UNIVERSITY · PI Vadim Y Arshavsky · 1985 to 2026
$19.3M
Basic Immunology Training ProgramT32AI052077 · NIAID · DUKE UNIVERSITY · PI KRANGEL, MICHAEL S · 2002 to 2024
$4.2M
Innate immune defenses against a cytosolic capsuleR01AI136920 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Edward A Miao · 2019 to 2026
$3.7M
Pyroptosis maintains the integrity of a granulomaR01AI175078 · NIAID · DUKE UNIVERSITY · PI Edward A Miao · 2023 to 2026
$2.6M
Intestinal epithelial cell exfoliation by caspasesR01AI139304 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MIAO, EDWARD A · 2018 to 2022
$2.2M
Natural killer cell cytotoxicity against intracellular bacteriaR01AI133236 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MIAO, EDWARD A · 2018 to 2022
$2.2M
Natural killer cell cytotoxicity against intracellular bacteriaR56AI133236 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MIAO, EDWARD A · 2017 to 2017
$291k
National Institute of Allergy and Infectious Diseases AI133236-04S1National Institute of Allergy and Infectious Diseases AI136920National Institute of Allergy and Infectious Diseases AI139304National Institute of Allergy and Infectious Diseases AI175078NEI NIH HHS P30 EY005722NIAID NIH HHS R01 AI133236NIAID NIH HHS R01 AI136920NIAID NIH HHS R01 AI139304NIAID NIH HHS R01 AI175078NIAID NIH HHS R56 AI133236NIAID NIH HHS T32 AI052077
6 · The paper itself

Abstract

Granulomas are defined by the presence of organized layers of immune cells that include macrophages. Granulomas are often characterized as a way for the immune system to contain an infection and prevent its dissemination. We recently established a mouse infection model where

Indexed as

ChemokinesGranulomaImmunity, InnateAnimalsChromobacteriumDisease Models, AnimalGene Expression ProfilingGram-Negative Bacterial InfectionsLiverMacrophagesMiceMice, Inbred C57BLMice, KnockoutReceptors, CCR2Ccr2 protein, mouseChemokinesReceptors, CCR2CCR2chemokinesChromobacterium violaceumgranulomaimmunologyinfectious diseaseinflammationmicrobiologymouse

Identifiers

PMID39541153
PMCPMC11563579

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.