Evidence map›Paper›PMID 39540968›Full record

ArticleOdontology2025

Effect of hinokitiol in ameliorating oral cancer: in vitro and in silico evidences.

Anitha Roy, Binoy Varghese Cheriyan, Elumalai Perumal, Kannan Rr Rengasamy, Shanmugam Anandakumar

Abstract read
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Article in Odontology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anitha RoyCenter for Transdisciplinary Research, Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, SIMATS, Chennai, Tamil Nadu, 600077, India.ORCID http://orcid.org/0000-0002-8631-0936
Binoy Varghese CheriyanDepartment of Pharmaceutical Chemistry, Saveetha College of Pharmacy, Saveetha Institute of Medical and Technical Sciences, SIMATS, Chennai, Tamil Nadu, 602105, India. lallybinoy@gmail.com.ORCID http://orcid.org/0000-0003-0830-6816
Elumalai PerumalCancer Genomics lab, Center for Global Health Research, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, SIMATS, Chennai, Tamil Nadu, 602105, India.ORCID http://orcid.org/0000-0003-3627-5527
Kannan Rr RengasamyLaboratory of Natural Products and Medicinal Chemistry (LNPMC), Center for Global Health Research, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, SIMATS, Chennai, Tamil Nadu, 602105, India.ORCID https://orcid.org/0000-0001-7205-7389
Shanmugam AnandakumarDepartment of Microbiology, Dr. ALM Post Graduate Institute of Basic Medical Science, University of Madras, Chennai, Tamil Nadu, 600113, India.ORCID http://orcid.org/0000-0003-3306-7589

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study aimed to evaluate the anticancer potential of hinokitiol in treating oral cancer by using in vitro models and examining its interaction with the Pim-1 protein through in silico methods. Hinokitiol was applied to KB-1 oral squamous carcinoma cells, where the half-maximal inhibitory concentrations (IC

Indexed as

Antineoplastic AgentsCarcinoma, Squamous CellMonoterpenesMouth NeoplasmsTropoloneAnimalsApoptosisCell CycleCell Line, TumorComputer SimulationFlow CytometryHumansIn Vitro TechniquesMiceMolecular Docking SimulationProto-Oncogene Proteins c-pim-1Antineoplastic Agentsbeta-thujaplicinMonoterpenesProto-Oncogene Proteins c-pim-1TropoloneHinokitiolMolecular dynamicsOral cancerPim-1

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.