Evidence map›Paper›PMID 39540951›Full record

ArticleNeurochemical research2024

Effects of Acute Haloperidol Treatment on Dopaminergic Markers, GAD

Getulio Nicola Bressan, Talita Rodrigues, Maria Eduarda Brandli da Silva, Maria Rosa Chitolina Schetinger, Rahisa Scussel, Ricardo Andrez Machado-de-Ávila, Jéssica da Silva Abel, Roselei Fachinetto

Abstract read
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In one paragraph

Article in Neurochemical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Getulio Nicola BressanPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica Toxicológica, Universidade Federal de Santa Maria, RS, Brazil.
Talita RodriguesPrograma de Pós-Graduação em Farmacologia, Universidade Federal de Santa Maria, RS, Brazil.
Maria Eduarda Brandli da SilvaCurso de Farmácia, Universidade Federal de Santa Maria, RS, Brazil.
Maria Rosa Chitolina SchetingerPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica Toxicológica, Universidade Federal de Santa Maria, RS, Brazil.
Rahisa ScusselPrograma de Pós-Graduação em Ciências da Saúde, Universidade do Extremo Sul Catarinense, Criciúma, SC, Brazil.
Ricardo Andrez Machado-de-ÁvilaPrograma de Pós-Graduação em Ciências da Saúde, Universidade do Extremo Sul Catarinense, Criciúma, SC, Brazil.
Jéssica da Silva AbelPrograma de Pós-Graduação em Ciências da Saúde, Universidade do Extremo Sul Catarinense, Criciúma, SC, Brazil.
Roselei FachinettoPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica Toxicológica, Universidade Federal de Santa Maria, RS, Brazil. roselei.fachinetto@ufsm.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vacuous chewing movements (VCM) have been utilized as an experimental model of orofacial dyskinesia (OD) in rodents to study the underlying molecular mechanisms related to tardive dyskinesia (TD). This study aimed to investigate if the acute treatment with haloperidol can alter components of the dopaminergic synapse or its modulators such as glutamic acid decarboxylase (GAD

Indexed as

DopamineGlutamate DecarboxylaseHaloperidolRats, WistarReceptor, Adenosine A2AAnimalsAntipsychotic AgentsBiomarkersDopamine Plasma Membrane Transport ProteinsMaleRatsAntipsychotic AgentsBiomarkersDopamineDopamine Plasma Membrane Transport ProteinsGlutamate Decarboxylaseglutamate decarboxylase 1HaloperidolReceptor, Adenosine A2AA2A receptorDopamineGAD67HaloperidolMAO-B activity

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.