Evidence map›Paper›PMID 39540772›Full record

ArticlemBio2024

Whole-blood model reveals granulocytes as key sites of dengue virus propagation, expanding understanding of disease pathogenesis.

Hansa Praneechit, Somchai Thiemmeca, Dararat Prayongkul, Kessiri Kongmanas, Dumrong Mairiang, Nuntaya Punyadee, Adisak Songjaeng, Nattaya Tangthawornchaikul, Nasikarn Angkasekwinai, Kanokwan Sriruksa and 4 more

Abstract read
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Innate Immune and Inflammatory Responses to Dengue Virus Infection.Current topics in microbiology and immunology · 2026
    Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hansa Praneechit *Graduate Program in Immunology, Department of Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Somchai Thiemmeca *Division of Dengue Hemorrhagic Fever Research, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID 0000-0002-6720-1435
Dararat PrayongkulDivision of Dengue Hemorrhagic Fever Research, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Kessiri KongmanasDivision of Dengue Hemorrhagic Fever Research, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Dumrong MairiangSiriraj Center of Research Excellence in Dengue and Emerging Pathogens, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Nuntaya PunyadeeDivision of Dengue Hemorrhagic Fever Research, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Adisak SongjaengDivision of Dengue Hemorrhagic Fever Research, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Nattaya TangthawornchaikulMolecular Biology of Dengue and Flaviviruses Research Team, Medical Molecular Biotechnology Research Group, National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Bangkok, Thailand.
Nasikarn AngkasekwinaiDepartment of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Kanokwan SriruksaPediatric Department, Khon Kaen Hospital, Ministry of Public Health, Khon Kaen, Thailand.
Yupin SuputtamongkolDepartment of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Wannee LimpitikulPediatric Department, Songkhla Hospital, Ministry of Public Health, Songkhla, Thailand.
John P AtkinsonDivision of Rheumatology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
Panisadee AvirutnanDivision of Dengue Hemorrhagic Fever Research, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID 0000-0003-0053-3045

Funding

Defining the Complosome in Human Cells, Tissues and Disease StatesR35GM136352 · NIGMS · WASHINGTON UNIVERSITY · PI ATKINSON, JOHN · 2020 to 2024
$2.0M
HHS | NIH | National Institute of General Medical Sciences (NIGMS) R35-GM136352-01Mahidol University (MU) R016010008MU | Faculty of Medicine Siriraj Hospital, Mahidol University (Siriraj Hospital) R016234004MU | Faculty of Medicine Siriraj Hospital, Mahidol University (Siriraj Hospital) Research Excellence Development (RED)National Research and Innovation Fund (NSRF) FF-027/2566NIGMS NIH HHS R35 GM136352Royal Golden Jubilee (RGJ) Ph.D. Programme (RGJ-Ph.D. programme) PHD/0026/2557
6 · The paper itself

Abstract

Dengue virus (DENV) infection poses a significant global health threat, yet our understanding of its immunopathogenesis remains incomplete due to limitations of existing models. Here, we establish an

Indexed as

DengueDengue VirusGranulocytesB-LymphocytesHumansKiller Cells, NaturalMonocytesT-LymphocytesViral TropismVirus Replicationdengue target cellsdengue virusgranulocytesin vitro whole-blood infection modelneutrophils

Identifiers

PMID39540772
PMCPMC11633123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.