ArticleJournal of applied clinical medical physics2025
Surrogate gating strategies for the Elekta Unity MR-Linac gating system.
Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Dosimetric Evaluation of MR-Guided IMRT and VMAT Techniques for Early-Stage Glottic Cancer: A Pilot Comparative Planning Study.Medicina (Kaunas, Lithuania) · 2026Article
- Optimal timing of the cumulative dose and factors related to acute urinary toxicity in prostate cancer treated using magnetic resonance linear accelerator.Radiological physics and technology · 2026Article
- MR-guided stereotactic radiosurgery of an intracardiac tumoral thrombus using comprehensive motion management.Clinical and translational radiation oncology · 2026Article
- Synthetic CT imaging for pelvic and abdominal MR-only radiotherapy: Clinical validation on a 1.5T MR-Linac.Journal of applied clinical medical physics · 2026Article
- Magnetic Resonance Guided Radical Radiation Therapy for Prostate Cancer in the Presence of Bilateral Hip Prostheses: First Experience With a 1.5 T Magnetic Resonance Linear Accelerator.Advances in radiation oncology · 2026Article
- Quantifying intrafractional colon tumor motion on 1.5 T MR-linac cine-MRI and applying anisotropic residual-motion margins for SBRT.Radiation oncology (London, England) · 2026Observational
- Optical Flow-Guided Analysis of Intrafractional Anatomical Variations in Pancreatic Tumors and Organs at Risk During Magnetic Resonance-Guided Adaptive Radiation Therapy Under Abdominal Compression.Advances in radiation oncology · 2026Article
- Balancing dose preservation and treatment efficiency in motion-managed magnetic resonance image-guided radiotherapy of pancreatic cancer.Physics and imaging in radiation oncology · 2026Article
- Development and evaluation of deep learning models for estimating the organ at-risk dose constraint from two-dimensional cine magnetic resonance imaging scans during irradiation.Journal of applied clinical medical physics · 2025Article
- Article
- Optimizing Motion Management and Baseline Shifts in Magnetic Resonance-Guided Spine Stereotactic Body Radiation Therapy.Cancers · 2025Article
- Development of in-house software to process real-time cine magnetic resonance images acquired during 1.5 T MR-guided radiation therapy.Scientific reports · 2025Article
- Improving efficiency in lung SAbR planning using integrated tools for X-ray based adaptive radiotherapy.Journal of applied clinical medical physics · 2025Article
- Surrogate gating strategies for the Elekta Unity MR-Linac gating system.Journal of applied clinical medical physics · 2025Article
- Real-time tracking of lung tumors using a 1.5T Elekta Unity MR-Linac: first clinical experiences.Frontiers in oncology · 2025Article
- Validating a T1-weighted cine MRI for a 1.5T MR-Linac with temporal resolution appropriate for respiratory motion.Frontiers in oncology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMRI-guided adaptive radiotherapy can directly monitor the anatomical positioning of the intended target during treatment with no additional imaging dose. Elekta has recently released its comprehensive motion management (CMM) solution that enables automatic radiation beam-gating on the Unity MR-Linac. Easily visualized targets that are distinct from the surrounding anatomy can be used to drive automatic gating decisions from the MRI cine imaging. However, poorly visualized targets can compromise the tracking and gating capabilities and may require surrogate tracking structures. This work presents strategies to generate robust tracking surrogates for a variety of treatment sites, enabling a wider application of CMM.
methodsSurrogate tracking strategies were developed from a cohort of patients treated using the CMM system on the Unity MR-Linac for treatment sites of the lung, pancreas, liver, and prostate. These sites posed challenging visualization or tracking of the primary target thereby compromising the tracking accuracy. Surrogate structures were developed using site-specific strategies to improve the imaging textured detail within the tracking volume while avoiding the dynamic overwhelming hypo- or hyper-intense anatomical structures. These surrogate volumes were applied within the anatomical positioning monitoring system as a proxy that drove the CMM gating decisions on the treatment unit.
resultsRobust site-specific surrogate structures were developed. Surrogate tracking structures for centrally located thoracic targets were created by expanding the target peripherally away from the heart and great vessels and into the lung. Pancreas surrogates required a vertically expanded column intersecting with the inferior liver edge. For the liver and prostate, surrogate structures consisted of a uniform expansion of the target, with liver surrogates intersecting the proximal liver edge or diaphragm while avoiding nearby ribs.
conclusionThese surrogate strategies have enabled the gating of complex moving targets among different treatment sites at our institution.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.