ArticleThe American journal of bioethics : AJOB2025
Digital Doppelgängers and Lifespan Extension: What Matters?
Article in The American journal of bioethics : AJOB, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Organ donation and brain preservation after assisted dying: case report and considerations for a potential pathway.BMC medical ethics · 2026Article
- Alzheimer's Disease and MERC Dysfunction: Integrating Mechanisms, Biomarkers, and Therapeutic Strategies.Molecular neurobiology · 2026Review
- Article
- The Many Faces of Indeterminacy in Interactive Deadbots.Philosophy & technology · 2026Article
- Do GenAI avatars open new responsibility gaps?AI & society · 2026Article
- The Enduring Promise of Personalising Patient Preference Prediction.Neuroethics · 2026Review
- AI-assisted rational decision-making.Synthese · 2026Article
- The Specter of Corporate Necromancy: Who Controls the Dead in the Age of Digital Doppelgängers?The American journal of bioethics : AJOB · 2025Article
- Bytes the Dust: Normative Notions in Decommissioning Digital Doppelgängers.The American journal of bioethics : AJOB · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
There is an ongoing debate about the ethics of research on lifespan extension: roughly, using medical technologies to extend biological human lives beyond the current "natural" limit of about 120 years. At the same time, there is an exploding interest in the use of artificial intelligence (AI) to create "digital twins" of persons, for example by fine-tuning large language models on data specific to particular individuals. In this paper, we consider whether digital twins (or digital doppelgängers, as we refer to them) could be a path toward a kind of life extension-or more precisely, a kind of
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.