Evidence map›Paper›PMID 39540393›Full record

ArticleOncology reports2025

METTL3‑mediated N6‑methyladenosine modification of MMP9 mRNA promotes colorectal cancer proliferation and migration.

Jie Chen, Henglan Wu, Ting Zuo, Jianming Wu, Zhiheng Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. The mMolecular biomedicine · 2025
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jie Chen *Department of Central Laboratory, The First Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang 314000, P.R. China.
Henglan Wu *Department of Nephrology, The First Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang 314000, P.R. China.
Ting ZuoDepartment of Anesthesia Surgery, The First Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang 314000, P.R. China.
Jianming WuDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang 314000, P.R. China.
Zhiheng ChenDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang 314000, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N6‑methyladenosine (m

Indexed as

AdenosineCell MovementCell ProliferationColorectal NeoplasmsGene Expression Regulation, NeoplasticMatrix Metalloproteinase 9MethyltransferasesRNA, MessengerAnimalsApoptosisCell Line, TumorFemaleHumansMaleMiceMice, Inbred BALB CAdenosineMatrix Metalloproteinase 9MethyltransferasesMETTL3 protein, humanMMP9 protein, humanN-methyladenosineRNA, Messengercolorectal cancermatrix metallopeptidase‑9methyltransferase‑like 3migrationN6‑methyladenosineproliferation

Identifiers

PMID39540393
PMCPMC11576960

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.