Evidence map›Paper›PMID 39540141›Full record

ArticleHemaSphere2024

Results of the prospective EORTC Children Leukemia Group study 58081 in precursor B- and T-cell acute lymphoblastic leukemia.

Carine Domenech, Michal Kicinski, Barbara De Moerloose, Caroline Piette, Wadih A Chahla, Laure Kornreich, Marlène Pasquet, Anne Uyttebroeck, Alexandre Theron, Marilyne Poirée and 15 more

Abstract read
In one paragraph

Article in HemaSphere, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Cutaneous Hematologic Neoplasms in Children: Overview and Update.Dermatopathology (Basel, Switzerland) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Carine DomenechDepartment of Pediatric Hematology-Oncology, Institut d'Hématologie et d'Oncologie Pédiatrique, Hospices Civils de Lyon Université Lyon1 Lyon France.ORCID 0000-0002-9349-4139
Michal KicinskiDepartment of Statistic EORTC Headquarters Brussels Belgium.
Barbara De MoerlooseDepartment of Pediatric Hematology-Oncology Ghent University Hospital Ghent Belgium.
Caroline PietteDepartment of Paediatrics, Division of Haematology-Oncology University Hospital Liège and University of Liège Liège Belgium.
Wadih A ChahlaDepartment of Pediatric Hematology-Oncology CHU Lille France.
Laure KornreichDepartment of Hemato-Oncology HUDERF-HUB (ULB) Brussels Belgium.
Marlène PasquetDepartment of Hematology Children's Hospital Toulouse France.
Anne UyttebroeckDepartment of Pediatrics University Hospital Gasthuisberg Leuven Belgium.
Alexandre TheronDepartment of Pediatric Hematology Oncology CHU de Montpellier Montpellier France.
Marilyne PoiréeDepartment of Hematology CHU Nice France.
Chloé ArfeuilleDépartement de Génétique Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Robert Debré Paris France.
Marleen BakkusDepartment of Molecular Hematology UZ Brussel Brussels Belgium.
Nathalie GrardelDepartment of Genetics-Hematology CHU Lille France.
Catherine PaillardDepartment of Paediatric Haematology and Oncology CHU Hautepierre Strasbourg.
Claire FreyconDepartment of Pediatrics CHRU La Tronche Grenoble France.
Frédéric MillotDepartment of Pediatric Hematology-Oncology CHU Poitiers France.
Pauline SimonDepartment of Pediatric Hematology-Oncology CHRU Besançon France.
Pierre PhilippetDepartment of Pediatric Hemato-Oncology CHC MontLégia Liège Belgium.
Claire PluchartDepartment of Hematology American Hospital Reims France.
Stefan SuciuDepartment of Statistic EORTC Headquarters Brussels Belgium.
Pierre RohrlichDepartment of Hematology CHU Nice France.
Alina FersterDepartment of Hemato-Oncology HUDERF-HUB (ULB) Brussels Belgium.
Yves BertrandDepartment of Pediatric Hematology-Oncology, Institut d'Hématologie et d'Oncologie Pédiatrique, Hospices Civils de Lyon Université Lyon1 Lyon France.
Hélène CavéDépartement de Génétique Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Robert Debré Paris France.ORCID 0000-0003-2840-1511
Children's Leukemia Group (CLG) of the European Organization for Research and Treatment of Cancer (EORTC)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, we report the results of the prospective cohort study EORTC-CLG 58081 and compare them to the control arm of the randomized phase 3 trial EORTC-CLG 58951, on which treatment recommendations were built. In both studies, patients aged 1-18 years with

Identifiers

PMID39540141
PMCPMC11558101

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.