Evidence map›Paper›PMID 39540107›Full record

ArticleAPL bioengineering2024

Harmonic imaging for nonlinear detection of acoustic biomolecules.

Rohit Nayak, Mengtong Duan, Bill Ling, Zhiyang Jin, Dina Malounda, Mikhail G Shapiro

Abstract read
In one paragraph

Article in APL bioengineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Acoustic percolation switches enable targeted drug delivery controlled by diagnostic ultrasound.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Rohit NayakDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.ORCID https://orcid.org/0000-0002-4353-6951
Mengtong DuanDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125, USA.ORCID https://orcid.org/0000-0002-1601-8876
Bill LingDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.ORCID https://orcid.org/0000-0002-1276-7204
Zhiyang JinAndrew and Peggy Cherng Department of Medical Engineering, California Institute of Technology, Pasadena, California 91125, USA.ORCID https://orcid.org/0000-0002-4411-6991
Dina MaloundaDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.ORCID https://orcid.org/0000-0001-7086-9877

Funding

Biogenic Gas Nanostructures As Molecular Imaging Reporters For UltrasoundR01EB018975 · NIBIB · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI Mikhail Shapiro · 2014 to 2026
$5.9M
NIBIB NIH HHS R01 EB018975
6 · The paper itself

Abstract

Gas vesicles (GVs) based on acoustic reporter genes have emerged as potent contrast agents for cellular and molecular ultrasound imaging. These air-filled, genetically encoded protein nanostructures can be expressed in a variety of cell types

Identifiers

PMID39540107
PMCPMC11560287

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.