Evidence map›Paper›PMID 39539988›Full record

ArticleDermatology reports2024

Annular elastolytic giant cell granuloma after COVID-19 vaccination.

Viviana Lora, Arianna Lamberti, Monia Di Prete, Dario Graceffa, Carlo Cota

Abstract readCase Reports
In one paragraph

Article in Dermatology reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Viviana LoraDermatology Unit, San Gallicano Dermatological Institute, IRCCS, Rome.
Arianna LambertiDermatopathology Unit, San Gallicano Dermatological Institute, IRCCS, Rome.
Monia Di PreteDermatopathology Unit, San Gallicano Dermatological Institute, IRCCS, Rome.
Dario GraceffaDermatology Unit, San Gallicano Dermatological Institute, IRCCS, Rome.
Carlo CotaDermatopathology Unit, San Gallicano Dermatological Institute, IRCCS, Rome.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pandemic of SARS-CoV-2 during the first years of the 2020s led to a great commitment to develop effective vaccines. Despite the good safety and tolerability profile, vaccines may trigger a broad spectrum of cutaneous side effects. Granulomatous dermatitis has been rarely reported after SARS-CoV-2 mRNA vaccines, but no cases of annular elastolytic giant cell granuloma have been described. Moreover, in our case, it was also associated with a central area of mid-dermal elastolysis, confirming the strong association between these two diseases already reported in the literature. The observation of occasional eosinophils within the infiltrate and the presentation of the cutaneous eruption a few days after the administration of the second dose of the Pfizer/BioNTech (BNT162b2) vaccine are highly suggestive of a drug-related eruption. To our knowledge, this is the first report in the literature of an annular elastolytic giant cell granuloma as an adverse effect of the SARS-CoV-2 vaccination.

Indexed as

COVID-19 vaccinationelastic fiberselastophagocytosisgranulomatous dermatitismid-dermal elastolysis

Identifiers

PMID39539988
PMCPMC11558312

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.