Evidence map›Paper›PMID 39539945›Full record

ArticlePulmonary circulation2024

Effects of dopamine β-hydroxylase inhibition in pressure overload-induced right ventricular failure.

Stine Andersen, Julie Sørensen Axelsen, Anders H Nielsen-Kudsk, Janne Schwab, Caroline D Jensen, Steffen Ringgaard, Asger Andersen, Rowan Smal, Aida Llucià-Valldeperas, Frances Handoko de Man and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pulmonary circulation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Stine AndersenDepartment of Cardiology Aarhus University Hospital Aarhus Denmark.ORCID https://orcid.org/0000-0002-7153-1170
Julie Sørensen AxelsenDepartment of Cardiology Aarhus University Hospital Aarhus Denmark.
Anders H Nielsen-KudskDepartment of Cardiology Aarhus University Hospital Aarhus Denmark.
Janne SchwabDepartment of Cardiology Aarhus University Hospital Aarhus Denmark.
Caroline D JensenDepartment of Cardiology Aarhus University Hospital Aarhus Denmark.
Steffen RinggaardDepartment of Clinical Medicine, MR Research Centre Aarhus University Aarhus Denmark.
Asger AndersenDepartment of Cardiology Aarhus University Hospital Aarhus Denmark.ORCID https://orcid.org/0000-0002-9102-3130
Rowan SmalDepartment of Pulmonology Amsterdam University Medical Centre Amsterdam The Netherlands.
Aida Llucià-ValldeperasDepartment of Pulmonology Amsterdam University Medical Centre Amsterdam The Netherlands.
Frances Handoko de ManDepartment of Pulmonology Amsterdam University Medical Centre Amsterdam The Netherlands.
Bruno IgrejaDepartment of Research BIAL, Portela & Cª, S.A. Coronado S. Romão e S. Mamede Portugal.
Nuno PiresDepartment of Research BIAL, Portela & Cª, S.A. Coronado S. Romão e S. Mamede Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Activation of the sympathetic nervous system is observed in pulmonary arterial hypertension patients. This study investigates whether inhibiting the conversion of dopamine into noradrenaline by dopamine

Indexed as

animal studydopamine β‐hydroxylasenoradrenalineright heart failuresympathetic nervous system

Identifiers

PMID39539945
PMCPMC11558268

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.