Evidence map›Paper›PMID 39539926›Full record

ArticleInternational journal of general medicine2024

A Composite Index for Distinguishing Benign and Malignant Obstructive Jaundice.

Hao Peng, Jixue Li, Xiaoru Zhou, Zhewen Nong, Ruiying Zhang, Pei Lu, Shasha Ye, Liping Lei, Chuang Qin, Jiangfa Li

Abstract read
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Article in International journal of general medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Hao Peng *Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, 541001, People's Republic of China.
Jixue Li *Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, 541001, People's Republic of China.
Xiaoru ZhouDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, 541001, People's Republic of China.
Zhewen NongDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, 541001, People's Republic of China.
Ruiying ZhangDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, 541001, People's Republic of China.
Pei LuDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, 541001, People's Republic of China.
Shasha YeDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, 541001, People's Republic of China.
Liping LeiDepartment of Geriatric Medicine, The Affiliated Hospital of Guilin Medical University, Guilin, 541001, People's Republic of China.
Chuang QinDepartment of Hepatobiliary and Pancreatic Surgery, Liuzhou People's Hospital, Liuzhou, 545001, People's Republic of China.ORCID 0000-0002-7296-914X
Jiangfa LiDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, 541001, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore a more effective and practical comprehensive index for differentiating benign from malignant obstructive jaundice by analyzing the clinical data of patients with benign obstructive jaundice (BJ) group and malignant obstructive jaundice (MJ) group. Methods: A retrospective analysis was conducted on the clinical data of 339 patients with obstructive jaundice. The cases were divided into two data sets: training cohort and validation cohort. The cases were divided into two groups: malignant and benign obstructive jaundice group. Logistic regression analysis was used to build a prediction model for judging the nature of obstructive jaundice, and the prediction model was verified using the validation cohort. Results: Multivariate analysis revealed that CEA, TBIL, and NLR were independent factors in malignant obstructive jaundice. A comprehensive index for differentiating benign from malignant obstructive jaundice was established based on these indicators. The sensitivity, specificity, and receiver operating characteristic curve of this model for differentiating benign from malignant obstructive jaundice were 79.57%, 93.26%, and 0.920, respectively. Conclusion: The prediction model based on the comprehensive index of CEA, TBIL, and NLR has a higher accuracy in differentiating malignant obstructive jaundice.

Indexed as

comprehensive indexdifferentiation diagnosisobstructive jaundice

Identifiers

PMID39539926
PMCPMC11559646

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