Evidence map›Paper›PMID 39539730›Full record

ArticleBioactive materials2024

Gelatin and lipidoid integrate to create

Abilash Gangula, Dhananjay Suresh, Agasthya Suresh Babu, Zhaohui Li, Anandhi Upendran, Raghuraman Kannan

Abstract read
In one paragraph

Article in Bioactive materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Abilash GangulaDepartment of Radiology, University of Missouri, Columbia, MO, 65212, USA.
Dhananjay SureshDepartment of Radiology, University of Missouri, Columbia, MO, 65212, USA.
Agasthya Suresh BabuDepartment of Bioengineering, University of Missouri, Columbia, MO, 65212, USA.
Zhaohui LiDepartment of Bioengineering, University of Missouri, Columbia, MO, 65212, USA.
Anandhi UpendranDepartment of Medical Pharmacology and Physiology, University of Missouri, Columbia, MO, 65212, USA.
Raghuraman KannanDepartment of Radiology, University of Missouri, Columbia, MO, 65212, USA.

Funding

Towards Translation of MU-CN29: New Therapeutic Nanoparticle for Drug-Resistant NSCLCR01CA274677 · NCI · UNIVERSITY OF MISSOURI-COLUMBIA · PI KANNAN, RAGHURAMAN · 2022 to 2025
$2.3M
NCI NIH HHS R01 CA274677
6 · The paper itself

Abstract

RNAi therapeutics possess the potential to cure many uncurable human diseases. For instance, RNAi therapeutics using liposomes showed remarkable survival benefits in patients with liver diseases. However, the extension of liposomes to deliver RNA to cure other ailments has largely been unsuccessful. Therefore, researchers are focusing on designing and testing different combinations of materials for versatile RNA delivery applications. Yet, an efficient and safe RNA delivery platform has not been identified. In this work, we have developed a new class of RNA-delivery vehicle called "Gelasomes," using an incongruous combination of gelatin and lipidoid to exploit each material's unique properties while overcoming their inherent limitations. The low

Identifiers

PMID39539730
PMCPMC11558258

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.