Evidence map›Paper›PMID 39539661›Full record

ArticleFrontiers in neurology2024

Can ischemic stroke patients with mTICI of 2b achieve similar outcomes compared to those with complete recanalization following endovascular therapy?

Zunbao Xu, Sahibjot Grewal, Mohammad Mofatteh, Adam A Dmytriw, Dongqing Zhao, Baikeng Chen, Haoyang Chen, Wanyi He, Rixin Luo, Zhenzhang Li and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zunbao XuNeuromedical Center Ward 2, The Affiliated Panyu Central Hospital, Guangzhou Medical University, Guangzhou, China.
Sahibjot GrewalNeurovascular Centre, Departments of Medical Imaging and Neurosurgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Mohammad MofattehSchool of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom.
Adam A DmytriwNeuroendovascular Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Dongqing ZhaoNeuromedical Center Ward 2, The Affiliated Panyu Central Hospital, Guangzhou Medical University, Guangzhou, China.
Baikeng ChenNeuromedical Center Ward 2, The Affiliated Panyu Central Hospital, Guangzhou Medical University, Guangzhou, China.
Haoyang ChenNeuromedical Center Ward 2, The Affiliated Panyu Central Hospital, Guangzhou Medical University, Guangzhou, China.
Wanyi HeNeuromedical Center Ward 2, The Affiliated Panyu Central Hospital, Guangzhou Medical University, Guangzhou, China.
Rixin LuoNeuromedical Center Ward 2, The Affiliated Panyu Central Hospital, Guangzhou Medical University, Guangzhou, China.
Zhenzhang LiCollege of Mathematics and Systems Science, Guangdong Polytechnic Normal University, Guangzhou, China.
Qiaowei LiNeuromedical Center Ward 2, The Affiliated Panyu Central Hospital, Guangzhou Medical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: Endovascular therapy (EVT) has been used as a standard treatment method for patients with large vessel ischemic stroke within 24 h of the onset. The extent of recanalization after EVT can be assessed using the modified thrombolysis in cerebral infarction (mTICI) scale as an accepted angiographic grading system. In this study, we aimed to investigate whether patients with a mTICI grade of 2b achieve similar outcomes compared to those with complete recanalization (mTICI of 3) following EVT for acute ischemic stroke. Methods: A retrospective analysis was conducted on 196 consecutive patients who underwent EVT in a comprehensive stroke center. In the final study, 176 patients were included based on the inclusion criteria. The primary outcome was the 3-month modified Rankin Scale (mRS) of 0-2 considered as a favorable outcome, while excellent outcomes were defined as mRS scores of 0-1. Results: Our data showed that 59.46% of patients in the mTICI 2b group achieved a favorable outcome, comparable to 58.99% observed in the mTICI 3 group ( Conclusion: Similar 3-month outcomes can be achieved for ischemic stroke patients undergoing EVT with a mTICI grade of 2b compared to those with a mTICI grade of 3. These data can help clinicians in setting realistic expectations and making informed decisions during EVT procedures.

Indexed as

acute ischemic strokeendovascular therapylarge vessel strokemTICIpatient outcome

Identifiers

PMID39539661
PMCPMC11557548

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