Evidence map›Paper›PMID 39539507›Full record

ArticleRoyal Society open science2024

Stochastic analysis of Ebola infection in small zoonotic niches.

Sena Mursel, Paolo Bocchini, Javier Buceta

Abstract read
In one paragraph

Article in Royal Society open science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sena MurselDepartment of Civil and Environmental Engineering, Lehigh University, Bethlehem, PA, USA.ORCID https://orcid.org/0000-0002-1021-274X
Paolo BocchiniDepartment of Civil and Environmental Engineering, Lehigh University, Bethlehem, PA, USA.ORCID https://orcid.org/0000-0002-5685-2283
Javier BucetaTheoretical and Computational Systems Biology Program, Institute for Integrative Systems Biology (I2SyBio), CSIC-UV, Paterna, Spain.ORCID https://orcid.org/0000-0003-1791-0011

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The size of fruit bat colonies ranges from dozens to hundreds of thousands of individuals, depending on the species. While a deterministic modelling approach is appropriate for large colonies, the role of population fluctuations can be all-important for small colonies. From this perspective, we analyse the infection dynamics in small zoonotic niches due to filoviruses, e.g. Ebola. To this end, we perform stochastic numerical simulations and analytical calculations. The inherent stochasticity in ecological processes may play a significant role in driving small populations towards extinction. Here, we reveal that fluctuations can either lead to virus eradication or to sustain infection compared with the deterministic dynamics, depending on the size of the zoonotic niche. Altogether, our findings reveal non-trivial stochastic effects, which can shed light on the infection dynamics in small- and medium-sized bat colonies and help design preventive measures for zoonotic diseases.

Indexed as

Ebolamathematical epidemiologystochastic SIR modelzoonosis

Identifiers

PMID39539507
PMCPMC11558069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.