Evidence map›Paper›PMID 39539004›Full record

ArticleJournal of the International Neuropsychological Society : JINS2024

Simplifying Complex Figure scoring: Data from the Emory Healthy Brain Study and initial clinical validation.

David W Loring, Najé Simama, Katherine Sanders, Jessica R Saurman, Liping Zhao, James J Lah, Felicia C Goldstein

Abstract readValidation Study
In one paragraph

Article in Journal of the International Neuropsychological Society : JINS, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Visual memory correlates with AD biomarkers in cognitively unimpaired individuals.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David W LoringDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0003-2497-1074
Najé SimamaDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
Katherine SandersDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
Jessica R SaurmanDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0002-2539-9711
Liping ZhaoDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health (Emory University), Atlanta, GA, USA.ORCID 0000-0003-3100-8454
James J LahDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0002-8810-620X
Felicia C GoldsteinDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0003-2688-3617

Funding

The Emory Healthy Brain Study: Discovering Predictive Biomarkers for Alzheimer's DiseaseR01AG070937 · NIA · EMORY UNIVERSITY · PI LAH, JAMES J · 2021 to 2025
$35.2M
NIA NIH HHS R01 AG070937
6 · The paper itself

Abstract

objectiveTo introduce the Emory 10-element Complex Figure (CF) scoring system and recognition task. We evaluated the relationship between Emory CF scoring and traditional Osterrieth CF scoring approach in cognitively healthy volunteers. Additionally, a cohort of patients undergoing deep brain stimulation (DBS) evaluation was assessed to compare the scoring methods in a clinical population.

methodThe study included 315 volunteers from the Emory Healthy Brain Study (EHBS) with Montreal Cognitive Assessment (MoCA) scores of 24/30 or higher. The clinical group consisted of 84 DBS candidates. Scoring time differences were analyzed in a subset of 48 DBS candidates.

resultsHigh correlations between scoring methods were present for non-recognition components in both cohorts (

conclusionsEmory CF scoring yields results that are highly correlated with traditional Osterrieth scoring, significantly reduces scoring time burden, and demonstrates greater sensitivity to memory decline in DBS candidates. Its efficiency and sensitivity make Emory CF scoring well-suited for broader implementation in clinical research.

Indexed as

Cognitive DysfunctionNeuropsychological TestsPattern Recognition, VisualRecognition, PsychologyAdultAgedDeep Brain StimulationFemaleHumansMaleMental RecallMental Status and Dementia TestsMiddle AgedYoung AdultAssessmentDeep brain stimulationInter-rater reliabilityRecognition memoryVisual constructionVisual memory

Identifiers

PMID39539004
PMCPMC13195541

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.