ArticleJournal of orthopaedic surgery and research2024
Biomechanical impact of progressive meniscal extrusion on the knee joint: a finite element analysis.
Article in Journal of orthopaedic surgery and research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- The Role of Ultrasound Versus Radiography in Knee Osteoarthritis: A Bilateral Comparative Study.Life (Basel, Switzerland) · 2026Article
- Medial meniscus extrusion during gait identifies altered knee mechanical loading in early osteoarthritis of the knee.Journal of experimental orthopaedics · 2026Article
- Medial Meniscus Root Repair Is Associated With Superior Outcomes As Compared With Partial Medial Meniscectomy at Minimum 5 Years: A Systematic Review and Meta-analysis.Orthopaedic journal of sports medicine · 2026Article
- Diagnostic value of postoperative magnetic resonance imaging in predicting clinical outcomes after meniscal repair: A retrospective cohort study.International orthopaedics · 2026Observational
- Investigation of acute and chronic injury mechanisms of the deltoid ligament: insights from finite element analysis and animal study.Journal of orthopaedic surgery and research · 2026Article
- Effect of Knee Joint Meniscus Tears on Joint Cartilage Contact and Pressure with Finite Element Analysis.Biomedicines · 2026Article
- Epigenetic silencing of SPHK1-IRF7 axis drives inflammaging in age-related meniscus degeneration via sphingolipid-immune dysregulation.Journal of orthopaedic surgery and research · 2025Article
- A Geometric Deep Learning Model for Real-Time Prediction of Knee Joint Biomechanics Under Meniscal Extrusion.Annals of biomedical engineering · 2025Review
- Compliant buffer layer achieves native-like cartilage stress in talar prosthesis: a finite element analysis study.Journal of orthopaedic surgery and research · 2025Article
- Influence of preoperative medial meniscus extrusion and subchondral bone marrow edema on outcomes after medial opening wedge high tibial osteotomy.Journal of orthopaedic surgery and research · 2025Article
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Authors and funding
6 authors.
Funding
Abstract
backgroundWhile measuring meniscal extrusion quantitatively is an early risk factor for knee osteoarthritis (KOA), the biomechanics involved in this process are not well understood. This study aimed to investigate the effects of varying degrees of medial and lateral meniscal extrusion and their material softening on knee osteoarthritis progression.
methodsFinite element analysis (FEA) was utilized to simulate varying degrees of meniscal extrusion (1-5 mm) in 72 knee joint models, representing progressive meniscal degeneration and material softening due to injury. Changes in von Mises stress of the cartilage and menisci and the load distribution on the tibial plateau's meniscus and cartilage were studied under balanced standing posture in both healthy and injured knees, and statistical analysis was performed using Spearman correlation.
resultsCompared to healthy knees, peak stress in medial compartment tissues increased by over 40% with 4 mm of medial meniscus extrusion, and in lateral compartment tissues with 2 mm of lateral meniscus extrusion. Meniscus extrusion reduced the contact load between the meniscus and femoral cartilage but increased it between the tibial and femoral cartilages, with a maximum increase up to fivefold. Spearman correlation analysis indicated that meniscal extrusion significantly affected peak stress and contact loads in the respective knee compartment (p < 0.001), with a lesser impact on the opposite compartment. Notably, medial meniscal extrusion also significantly increased peak stress in the lateral tibial cartilage (p < 0.05).
conclusionsThe quantitative analysis revealed that meniscal extrusion significantly affected the biomechanics of soft tissues within the same compartment, with limited impact on the opposite side. Specifically, Medial extrusion beyond 4 mm significantly affected the biomechanics of the medial compartment, while lateral extrusion over 2 mm had a similar impact on the lateral compartment. Meniscal softening, without altering joint contact characteristics, primarily affected the biomechanics of the meniscus itself, with minimal impact on other soft tissues.
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