ReviewWorld journal of pediatrics : WJP2024
Expert consensus for pertussis in children: new concepts in diagnosis and treatment.
Review in World journal of pediatrics : WJP, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Therapeutic Role of Hydroxyurea in Paediatric Hydroxyurea Pertussis:Sultan Qaboos University medical journal · 2025Pooled it
- Development and validation of a clinical severity prediction model for hospitalized children with pertussis.BMC infectious diseases · 2026Article
- Diagnostic Performance and Clinical Outcomes of Pertussis in Hospitalized Children in Relation to Available Vaccination Status: A Retrospective Cohort Study.Infectious diseases and therapy · 2026Article
- Epidemiological burden of pertussis in children in Asia: a review of 1990-2021 data and future projections.Translational pediatrics · 2026Article
- Pertussis: a retrospective analysis of cases observed in Mersin Türkiye, 2020 to 2024 evaluation of pertussis cases.BMC infectious diseases · 2026Article
- One Sample, Many Insights: The Epidemiological and Public Health Value of Multiplex PCR Respiratory Panels Following the End of the COVID-19 Pandemic.Microorganisms · 2026Article
- Charcoal agar interference in antibiotic susceptibility testing of Bordetella pertussis: evaluation and alternative methodologies.Annals of clinical microbiology and antimicrobials · 2026Article
- An Enzymatic Recombinase Amplification Coupled Lateral Flow Assay for Rapid, Visual, and Cost-Effective Detection of Bordetella pertussis.Current microbiology · 2026Article
- Severe Pertussis During Early Infancy from a High-Altitude Region: Two Clinical Cases and Literature Review.Journal of clinical medicine · 2026Article
- Article
- Atypical pertussis: Family cluster case series and primary care management strategies.Journal of family medicine and primary care · 2026Article
- Clinical characteristics analysis of pertussis and Mycoplasma pneumoniae infection in children.Frontiers in cellular and infection microbiology · 2026Article
- Clinical features, disease severity, and outcomes of pertussis in hospitalized children: A retrospective study from Serbia.PloS one · 2026Article
- Preliminary epidemiological and clinical profile of the 2024 pediatric pertussis outbreak: a retrospective analysis.Frontiers in pediatrics · 2026Article
- Clinical characteristics and macrolide resistance analysis of pertussis in children: a retrospective study.Frontiers in public health · 2026Article
- Practice variability in the management of critical pertussis: a multicenter survey of pediatric intensivists in the Arabian Gulf Cooperation Council region.Frontiers in pediatrics · 2026Article
- Breakthrough infections and incomplete vaccine efficacy drive pathogen immune escape.PloS one · 2026Article
- Parent-driven transmission, off-label SMZ-TMP, and severe pertussis prediction in infants under 2 months: a real-world observational cohort of 527 cases.Frontiers in pediatrics · 2026Article
- EEG and seizures of pertussis encephalopathy in infants.Frontiers in pediatrics · 2026Article
- Genomic insights into Bordetella pertussis evolution and macrolide resistance in Yiwu, China.BMC genomics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors.
Funding
Abstract
backgroundPertussis resurgence has been reported worldwide in the past two decades. Pertussis is still endemic and difficult to control though with universal vaccination in children. The resurgence may be related to multiple variables, such as increased disease awareness and laboratory tests, waning of immunity following vaccination, and/or genetic mutations of Bordetella pertussis. For better pertussis prevention, diagnosis, and management, we called up an expert panel to develop this expert consensus to provide new concepts in diagnosis and treatment for clinical practice. DATA SOURCES: The expert groups collected clinical evidence, summarized their clinical experiences, evaluated preliminary recommendations or guidelines, and then organized open-ended discussions to form the recommendations. This consensus was developed by reviewing the literature and studies in databases, including PubMed, Cochrane, EMBASE, the China Biomedical Database, and the Chinese Journal Full-text Database up to May 2024. The search terms included "pertussis" or "whooping cough", "children", "diagnosis", and "treatment".
resultsThe burden of pertussis has also changed from infants to school children and adults, and these age groups have consequently become the main source of infection for vulnerable population including infants and newborns. In China, a high prevalence of erythromycin-resistant Bordetella pertussis (ERBP) has been reported in the past decade. ERBP may lead to failed clinical empirical treatment with macrolides, which poses a great challenge for pertussis management and control. For better management of pertussis, a flow diagram for diagnosis and treatment of pertussis was presented in this consensus. This consensus also described the diagnostic criteria for pertussis, high-risk cases, and severe pertussis. Macrolides can still be used to treat confirmed erythromycin-sensitive B. pertussis (ESBP) infections, whereas oral trimethoprim-sulfamethoxazole therapy is the initial treatment option for children older than two months. For infants younger than two months, severe patients, or those exhibiting a high degree of sulfonamide allergy, intravenous administration of piperacillin or cefoperazone-sulbactam is advised.
conclusionsThis expert consensus provides a comprehensive guidance and a reference for the diagnosis and treatment of pertussis in children.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.