ArticleNature2025
Foundation models for fast, label-free detection of glioma infiltration.
Abstract readMulticenter Study
In one paragraph
Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.
0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
70 citing papers in PubMed.
- From spectroscopic analysis to clinical imaging: emerging applications and persistent challenges of raman spectroscopy in CTCs-based liquid biopsies.Annals of medicine · 2026Review
- 100-Second Large-Area Chemical Imaging by Integrated Four-Channel CARS Microscopy.Chemical & biomedical imaging · 2026Article
- Optical microscopy predictions of focal recurrence in glioblastoma.Science advances · 2026Article
- Ensemble learning of pathology foundation models for precision oncology.Cancer cell · 2026Article
- Shining a light on brain tumors: a review of Raman spectroscopy in the operating room.Journal of biomedical optics · 2026Review
- nnMIL: a generalizable multiple instance learning framework for computational pathology.Nature biomedical engineering · 2026Article
- Artificial intelligence in oncology: linking biological discovery to clinical utility.Molecular cancer · 2026Review
- Multimodal imaging and AI in brain tumor surgery: current tools and emerging integration.npj biomedical innovations · 2026Review
- Learning neuroimaging models from health system-scale data.Nature biomedical engineering · 2026Article
- From Label-Free Multiphoton Imaging to Pathological Reports: A Vision-Language Breast Cancer Margin Pathological Diagnosis System.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Navigating the Artificial Intelligence Revolution in Clinical Neurology: A New Multidisciplinary Task Force Within the European Academy of Neurology.European journal of neurology · 2026Article
- Foundation models in radiology: a primer for pediatric radiologists.Pediatric radiology · 2026Review
- PLANCK: super-multiplex optical imaging without labeling.bioRxiv : the preprint server for biology · 2026Article
- Contemporary surgical strategies for resection of intracranial gliomas.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026Review
- Intraoperative technological advances and new frontiers in precision glioma surgery.Journal of neuro-oncology · 2026Review
- Advancing AI for multi-omics and clinical data integration in basic and translational cancer research.Nature reviews. Cancer · 2026Review
- Review
- Multidisciplinary management of meningiomas in the era of precision oncology.Nature reviews. Clinical oncology · 2026Review
- A label-free nanoplasmonic biosensor for intraoperative discrimination of tumor margins in brain metastases surgery.Journal of neuro-oncology · 2026Article
- Multimodal integration of pathomics and clinical features improves recurrence risk prediction in pediatric medulloblastoma.Pediatric research · 2026Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors.
Akhil KondepudiMachine Learning in Neurosurgery Laboratory, Department of Neurosurgery, University of Michigan, Ann Arbor, MI, USA.
Melike PekmezciDepartment of Pathology, University of California, San Francisco, San Francisco, CA, USA.ORCID 0000-0003-2548-8359
Xinhai HouMachine Learning in Neurosurgery Laboratory, Department of Neurosurgery, University of Michigan, Ann Arbor, MI, USA.
Katie ScotfordDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, USA.
Cheng JiangMachine Learning in Neurosurgery Laboratory, Department of Neurosurgery, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0003-1759-4960
Akshay RaoMachine Learning in Neurosurgery Laboratory, Department of Neurosurgery, University of Michigan, Ann Arbor, MI, USA.
Edward S HarakeMachine Learning in Neurosurgery Laboratory, Department of Neurosurgery, University of Michigan, Ann Arbor, MI, USA.
Asadur ChowduryMachine Learning in Neurosurgery Laboratory, Department of Neurosurgery, University of Michigan, Ann Arbor, MI, USA.
Wajd Al-HolouDepartment of Neurosurgery, University of Michigan, Ann Arbor, MI, USA.
Lin WangMachine Learning in Neurosurgery Laboratory, Department of Neurosurgery, University of Michigan, Ann Arbor, MI, USA.
Aditya PandeyDepartment of Neurosurgery, University of Michigan, Ann Arbor, MI, USA.
Pedro R LowensteinDepartment of Neurosurgery, University of Michigan, Ann Arbor, MI, USA.
Maria G CastroDepartment of Neurosurgery, University of Michigan, Ann Arbor, MI, USA.
Lisa Irina KoernerDepartment of Neurosurgery, Medical University Vienna, Vienna, Austria.ORCID 0000-0002-9227-461X
Thomas Roetzer-PejrimovskyComprehensive Center for Clinical Neurosciences and Mental Health, Medical University of Vienna, Vienna, Austria.ORCID 0000-0001-8875-7304
Georg WidhalmDepartment of Neurosurgery, Medical University Vienna, Vienna, Austria.ORCID 0000-0001-6014-0273
Sandra Camelo-PiraguaDepartment of Pathology, University of Michigan, Ann Arbor, MI, USA.
Misha Movahed-EzaziDepartment of Pathology, Rutgers University, New Brunswick, NJ, USA.
Daniel A OrringerDepartment of Neurosurgery, New York University, New York, NY, USA.ORCID 0000-0001-6427-8376
Honglak LeeElectrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI, USA.
Christian FreudigerInvenio Imaging, Inc., Santa Clara, CA, USA.
Mitchel BergerDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, USA.
Shawn Hervey-JumperDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, USA. Shawn.Hervey-Jumper@ucsf.edu.ORCID 0000-0003-4699-260X
Todd HollonMachine Learning in Neurosurgery Laboratory, Department of Neurosurgery, University of Michigan, Ann Arbor, MI, USA. tocho@med.umich.edu.ORCID 0000-0001-5987-6531
Funding
MICHIGAN MEDICAL SCIENTIST TRAINING PROGRAMT32GM007863 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COLLINS, KATHLEEN L. · 1985 to 2024
$38.3MTransitioning Early Career Neurosurgeons to Scientific IndependenceK12NS080223 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI ESKANDAR, EMAD N · 2012 to 2022
$9.2MClinical Translation of Stimulated Raman HistologyR01CA226527 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ORRINGER, DANIEL · 2018 to 2025
$4.4MDeepSRH: Transforming Molecular Cancer Screening with Stimulated Raman Histology and Deep Neural NetworksR01CA292529 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HOLLON, TODD CHARLES, LEE, HONGLAK · 2025 to 2025
$2.3MCortical information loss in diffuse low-grade glioma infiltrated cortexR01NS137950 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Shawn L. Hervey-Jumper · 2024 to 2026
$1.2MSingle-cell optical phenotyping for diffuse gliomas using artificial intelligence and label-free microscopyF31NS135973 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Cheng Jiang · 2024 to 2026
$128kNCI NIH HHS R01 CA226527NCI NIH HHS R01 CA292529NIGMS NIH HHS T32 GM007863NINDS NIH HHS F31 NS135973NINDS NIH HHS K12 NS080223NINDS NIH HHS R01 NS137950
Abstract
A critical challenge in glioma treatment is detecting tumour infiltration during surgery to achieve safe maximal resection
Indexed as
Brain NeoplasmsGliomaHumansNeoplasm InvasivenessProspective StudiesROC CurveTime Factors
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What OpenQuestion holds
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LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.