Evidence map›Paper›PMID 39537869›Full record

ArticleScientific reports2024

Combined influence of quantum iterative reconstruction level and kernel sharpness on image quality in photon counting CT angiography of the upper leg.

Kristina Krompaß, Florian Andreas Goldbrunner, Viktor Hartung, Süleyman Ergün, Dominik Peter, Robin Hendel, Henner Huflage, Theresa Sophie Patzer, Jan-Lucca Hennes, Thorsten Alexander Bley and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kristina KrompaßDepartment of Diagnostic and Interventional Radiology, University Hospital of Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Germany.
Florian Andreas GoldbrunnerDepartment of Diagnostic and Interventional Radiology, University Hospital of Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Germany.
Viktor HartungDepartment of Diagnostic and Interventional Radiology, University Hospital of Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Germany.
Süleyman ErgünInstitute of Anatomy and Cell Biology, University of Würzburg, Würzburg, Germany.
Dominik PeterDepartment of General, Visceral, Transplant, Vascular, and Pediatric Surgery, University Hospital of Würzburg, Würzburg, Germany.
Robin HendelDepartment of Diagnostic and Interventional Radiology, University Hospital of Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Germany.
Henner HuflageDepartment of Diagnostic and Interventional Radiology, University Hospital of Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Germany.
Theresa Sophie PatzerDepartment of Diagnostic and Interventional Radiology, University Hospital of Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Germany.
Jan-Lucca HennesDepartment of Diagnostic and Interventional Radiology, University Hospital of Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Germany.
Thorsten Alexander BleyDepartment of Diagnostic and Interventional Radiology, University Hospital of Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Germany.
Jan-Peter GrunzDepartment of Diagnostic and Interventional Radiology, University Hospital of Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Germany.
Philipp GruschwitzDepartment of Diagnostic and Interventional Radiology, University Hospital of Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Germany. gruschwitz_p@ukw.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim was to evaluate the influence of different quantum iterative reconstruction (QIR) levels on the image quality of femoral photon-counting CT angiographies (PCD-CTA).Ultra-high resolution PCD-CTA were obtained from both extremities of five extracorporeally-perfused cadavers using constant tube voltage and maximum radiation dose (71.2 ± 11.0 mGy). Images were reconstructed with three kernels (Bv48, Bv60, Bv76) and the four available levels of QIR. Signal attenuation in the arterial lumen, muscle, and fat were measured. Contrast-to-noise ratios (CNR) and blurring scores were calculated for objective assessment. Six radiologists evaluated the subjective image quality using a pairwise comparison tool.Higher QIR level resulted in a decisive image noise reduction, especially with sharper convolution kernels (Bv60: Q1 11.5 ± 6.3 HU vs. Q4 8.4 ± 2.6 HU; p < 0.001). Largest improvement of CNR was recorded with ultra-sharp reconstructions (Bv76: Q1 20.2 ± 4.4 vs. Q4 28.0 ± 3.5; p < 0.001). Blurring decreased with higher QIR levels for soft Bv48, remained constant for medium Bv60, and increased for sharp Bv76 reconstructions. Subjective QIR level preference varied kernel depending, preferred combinations were: Bv48/Q4, Bv60/Q2, Bv76/Q3. Interrater agreement was excellent.Sharp kernels benefited most from noise reduction of higher QIR levels in lower extremity PCD-CTA. In sum, QIR level 3 provided the best objective and subjective image quality results.

Indexed as

Computed Tomography AngiographyPhotonsAgedCadaverFemaleHumansImage Processing, Computer-AssistedLegMaleRadiographic Image Interpretation, Computer-AssistedSignal-To-Noise Ratio

Identifiers

PMID39537869
PMCPMC11561153

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.