Evidence map›Paper›PMID 39537754›Full record

ArticleNature cell biology2024

A systemic effect for liver senescence.

Kuo Du, David Scott Umbaugh, Rajesh Kumar Dutta, Anna Mae Diehl

Abstract read
In one paragraph

Article in Nature cell biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kuo DuDepartment of Medicine, Duke University, Durham, NC, USA.
David Scott UmbaughDepartment of Medicine, Duke University, Durham, NC, USA.
Rajesh Kumar DuttaDepartment of Medicine, Duke University, Durham, NC, USA.
Anna Mae DiehlDepartment of Medicine, Duke University, Durham, NC, USA. annamae.diehl@duke.edu.ORCID http://orcid.org/0000-0003-1859-089X

Funding

Hepatic Lipotoxicity, Metabolic Homeostasis and NAFLD PathogenesisR56DK134334 · NIDDK · DUKE UNIVERSITY · PI DIEHL, ANNA MAE ELIZABETH · 2023 to 2023
$493k
Targeting Hepatocyte Senescence to Improve NAFLDK01DK135793 · NIDDK · DUKE UNIVERSITY · PI Kuo Du · 2024 to 2026
$433k
Senescent hepatocytes mediate reprogramming of immune cells in acute liver failureF31DK134197 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI UMBAUGH, DAVID SCOTT · 2023 to 2024
$46k
American Association for the Study of Liver Diseases (AASLD) 2021 AASLD Pinnacle AwardNIDDK NIH HHS F31 DK134197NIDDK NIH HHS K01 DK135793NIDDK NIH HHS R56 DK134334U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes & Digestive & Kidney Diseases) R01-DK07794U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes & Digestive & Kidney Diseases) R56-DK134334
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39537754
PMCPMC12159875

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.