Evidence map›Paper›PMID 39537727›Full record

ArticleScientific reports2024

Translational implications of a novel combination of iPRF and collagen scaffold for proliferation of gingival mesenchymal stem cells.

Komal K Ghadge, Sharath K Shetty, Avinash Kharat, Supriya Kheur, Anita Kulloli, Dharmarajan Gopalakrishnan, Ramesh Bhonde

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Komal K GhadgeDepartment of Periodontology and Oral Implantology, Dr. D Y Patil Dental College and Hospital, Dr D Y Patil Vidyapeeth, Pimpri, 411018, Pune, Maharashtra, India.
Sharath K ShettyDepartment of Periodontology and Oral Implantology, Dr. D Y Patil Dental College and Hospital, Dr D Y Patil Vidyapeeth, Pimpri, 411018, Pune, Maharashtra, India.
Avinash KharatDepartment of Regenerative Medicine Laboratory, Dr. D Y Patil Dental College and Hospital, Dr D Y Patil Vidyapeeth, Pimpri, 411018, Pune, Maharashtra, India.
Supriya KheurDepartment of Oral Pathology, Dr. D Y Patil Dental College and Hospital, Dr D Y Patil vidyapeeth, Pimpri, 411018, Pune, Maharashtra, India.
Anita KulloliDepartment of Periodontology and Oral Implantology, Dr. D Y Patil Dental College and Hospital, Dr D Y Patil Vidyapeeth, Pimpri, 411018, Pune, Maharashtra, India.
Dharmarajan GopalakrishnanDepartment of Periodontology and Oral Implantology, Dr. D Y Patil Dental College and Hospital, Dr D Y Patil Vidyapeeth, Pimpri, 411018, Pune, Maharashtra, India.
Ramesh BhondeDepartment of Regenerative Medicine Laboratory, Dr. D Y Patil Dental College and Hospital, Dr D Y Patil Vidyapeeth, Pimpri, 411018, Pune, Maharashtra, India. rrbhonde@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

"Tissue engineering," is a concept that involves the use of scaffolds, cells, and growth factors/signaling molecules in the field of regenerative medicine. The present study was carried out to evaluate the attachment and depth of penetration of the Gingival Mesenchymal Stem Cells (GMSCs) onto the collagen scaffold preconditioned with Fetal Bovine Serum (FBS), Injectable Platelet Rich Fibrin (i-PRF) and a combination of FBS with i-PRF using histological analysis and environmental scanning electron microscopy (ESEM) respectively. In the present study, commercially available collagen membranes were used as scaffolds and divided into 3 groups where Group I was preconditioned with FBS, Group II was preconditioned with i-PRF, and Group III with a combination of FBS and i-PRF. Scaffolds were then seeded with GMSCs and incubated in a CO

Indexed as

Cell ProliferationCollagenGingivaMesenchymal Stem CellsTissue ScaffoldsAnimalsCattleCells, CulturedHumansMicroscopy, Electron, ScanningPlatelet-Rich FibrinTissue EngineeringTranslational Research, BiomedicalCollagenCollagen ScaffoldFetal bovine serumGingival mesenchymal stem cellsGrowth factorsI-PRFTissue engineering

Identifiers

PMID39537727
PMCPMC11561316

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.