Evidence map›Paper›PMID 39537560›Full record

Observational studyBMJ open quality2024

Simulation with Monte Carlo methods to focus quality improvement efforts on interventions with the greatest potential for reducing PACU length of stay: a cross-sectional observational study.

James Harvey Jones, Neal Fleming

Abstract readObservational Study
In one paragraph

Observational study in BMJ open quality, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

James Harvey JonesDepartment of Anesthesiology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA jamesjns137@gmail.com.ORCID 0000-0003-2655-9067
Neal FlemingDepartment of Anesthesiology, University of California Davis, Davis, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTime and money are limited resources to pursue quality improvement (QI) goals. Computer simulation using Monte Carlo methods may help focus resources towards the most efficacious interventions to pursue.

methodsThis observational, cross-sectional study analysed the length of stay (LOS) for adult American Society of Anesthesiologists (ASA) 1-3 patients in the postanaesthesia care unit (PACU) at a major academic medical centre. Data were collected retrospectively from 1 April 2023 to 31 March 2024. Statistical analysis with Monte Carlo methods simulated the per cent reduction in PACU LOS following the elimination of postoperative nausea and vomiting (PONV), hypothermia (initial temperature<36°C), severe pain (pain score≥7) or moderate opioid use (≥ 50 mcg fentanyl or≥0.4 mg hydromorphone).

resultsThe PACU LOS of 7345 patients were included in this study. PONV was experienced by 10.29% of patients and was associated with a mean PACU LOS of 96.64 min (±33.98 min). Hypothermia was the least frequent complication, experienced by 8.93% of patients and was associated with a mean PACU LOS of 83.55 min (±35.99 min). Severe pain and moderate opioid use were seen in 34.05% and 40.83% of patients, respectively and were associated with PACU LOS that were shorter than those experienced by patients with PONV. Monte Carlo simulations demonstrated that the greatest impact on PACU LOS (12.5% (95% CI 12.0% to 13.0%)) would result from the elimination of moderate opioid use. DISCUSSION: Although PONV was associated with the longest PACU LOS, statistical simulation with Monte Carlo methods demonstrated the greatest per cent reduction in PACU LOS would result from the elimination of moderate opioid use, thus indicating the most efficacious project to pursue.

conclusionStatistical simulation with Monte Carlo methods can help guide QI teams to the most efficacious project or intervention to pursue.

Indexed as

Anesthesia Recovery PeriodComputer SimulationLength of StayMonte Carlo MethodPostoperative CareQuality ImprovementAdultAgedAnalgesics, OpioidCross-Sectional StudiesFemaleHumansMaleMiddle AgedRetrospective StudiesAnalgesics, OpioidAnaesthesiaHealthcare quality improvementQuality improvement

Identifiers

PMID39537560
PMCPMC11575234

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.