Evidence map›Paper›PMID 39537445›Full record

ReviewCurrent opinion in virology

Blood virome research in myalgic encephalomyelitis/chronic fatigue syndrome: challenges and opportunities.

Dominic Obraitis, Dawei Li

Abstract readReview
In one paragraph

Review in Current opinion in virology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dominic ObraitisDepartment of Immunology and Molecular Microbiology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA; Neuroscience and Behavior Program, Florida Atlantic University, Boca Raton, FL 33431, USA.
Dawei LiDepartment of Immunology and Molecular Microbiology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. Electronic address: dawei.li@ttuhsc.edu.

Funding

Research CoreU54AI178855 · NIAID · CORNELL UNIVERSITY · PI ANDREW W GRIMSON · 2023 to 2026
$9.4M
Endogenous retrovirus analyses in myalgic encephalomyelitisR21AI159710 · NIAID · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI LI, DAWEI · 2021 to 2022
$461k
Comprehensive analyses of endogenous retroviruses with severe chronic fatigue syndromeR03AI147084 · NIAID · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI LI, DAWEI · 2019 to 2020
$152k
NIAID NIH HHS R03 AI147084NIAID NIH HHS R21 AI159710NIAID NIH HHS U54 AI178855
6 · The paper itself

Abstract

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disease with a complex clinical presentation and an unknown etiology. Various viral infections have been proposed as potential triggers of ME/CFS onset, but no specific pathogen has been identified in all cases of postinfectious ME/CFS. The symptomatology of the postacute sequelae of SARS-CoV-2, or long COVID, mirrors that of ME/CFS, with nearly half of long COVID patients meeting ME/CFS diagnostic criteria. The influx of newly diagnosed patients has reinvigorated interest in ME/CFS pathogenesis research, with an emphasis on viral triggers. This review summarizes the current understanding of ME/CFS research on viral triggers, including blood virome screening studies. To further elucidate the molecular basis of ME/CFS, there is a need to develop innovative bioinformatics tools capable of analyzing complex virome data and integrating multiomics information.

Indexed as

COVID-19Fatigue Syndrome, ChronicViromeHumansSARS-CoV-2

Identifiers

PMID39537445
PMCPMC11795702

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.