Evidence map›Paper›PMID 39537182›Full record

ArticleJournal of atherosclerosis and thrombosis2025

Dairy Intake and All-Cause, Cancer, and Cardiovascular Disease Mortality Risk in A Large Japanese Population: A 12-Year Follow-Up of the J-MICC Study.

Naoko Miyagawa, Naoyuki Takashima, Akiko Harada, Aya Kadota, Keiko Kondo, Katsuyuki Miura, Nahomi Imaeda, Chiho Goto, Jun Otonari, Hiroaki Ikezaki and 24 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of atherosclerosis and thrombosis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. The doseFrontiers in nutrition · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Naoko MiyagawaDepartment of Preventive Medicine and Public Health, Keio University School of Medicine.
Naoyuki TakashimaDepartment of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine.
Akiko HaradaNCD Epidemiology Research Center, Shiga University of Medical Science.
Aya KadotaDepartment of Public Health, Shiga University of Medical Science.
Keiko KondoDepartment of Public Health, Shiga University of Medical Science.
Katsuyuki MiuraDepartment of Public Health, Shiga University of Medical Science.
Nahomi ImaedaDepartment of Nutrition, Faculty of Wellness, Shigakkan University.
Chiho GotoDepartment of Health and Nutrition, School of Health and Human Life, Nagoya Bunri University.
Jun OtonariDepartment of Psychosomatic Medicine Graduate School of Medical Sciences, Kyushu University.
Hiroaki IkezakiDepartment of General Internal Medicine, Kyushu University Hospital.
Keitaro TanakaDepartment of Preventive Medicine, Faculty of Medicine, Saga University.
Chisato ShimanoeDepartment of Pharmacy, Saga University Hospital.
Mako NagayoshiDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine.
Takashi TamuraDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine.
Yoko KuboDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine.
Yasufumi KatoDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine.
Yuriko N KoyanagiDivision of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute.
Hidemi ItoDivision of Cancer Information and Control, Aichi Cancer Center Research Institute.
Nobuaki MichihataCancer Prevention Center, Chiba Cancer Center Research Institute.
Yohko NakamuraCancer Prevention Center, Chiba Cancer Center Research Institute.
Shiroh TanoueDepartment of Epidemiology and Preventive Medicine, Kagoshima University Graduate School of Medical and Dental Sciences.
Rie IbusukiDepartment of International Island and Community Medicine, Kagoshima University Graduate School of Medical and Dental Sciences.
Sadao SuzukiDepartment of Public Health, Nagoya City University Graduate School of Medical Sciences.
Takeshi NishiyamaDepartment of Public Health, Nagoya City University Graduate School of Medical Sciences.
Etsuko OzakiDepartment of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine.
Isao WatanabeDepartment of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine.
Kiyonori KurikiLaboratory of Public Health, Division of Nutritional Sciences, School of Food and Nutritional Sciences, University of Shizuoka.
Takeshi WatanabeDepartment of Preventive Medicine, Tokushima University Graduate School of Biomedical Sciences.
Masashi IshizuDepartment of Preventive Medicine, Tokushima University Graduate School of Biomedical Sciences.
Asahi HishidaDepartment of Public Health, Aichi Medical University School of Medicine.
Yoshikuni KitaDepartment of Public Health, Shiga University of Medical Science.
Kenji WakaiDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine.
Keitaro MatsuoDivision of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute.
J-MICC Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimWe examined the association between dairy intake and all-cause, cancer, and cardiovascular disease mortality in a cohort of the general population followed up for 12 years across Japan.

methodsWe conducted a longitudinal cohort study of 79,715 participants from the Japan Multi-Institutional Collaborative Cohort study (57.2% women, mean age 54.7 years old). The amount of dairy (milk and yogurt) intake was determined using a validated short-food frequency questionnaire. The hazard ratio for mortality according to sex-specific tertile of dairy intake was calculated using Cox proportional hazards regression models with adjustment for potential confounding factors and dietary factors by sex.

resultsDuring the follow-up period (932,738 person-years), 3,723 participants died, including 2,088 cancer and 530 cardiovascular disease deaths. The highest tertile of total dairy intake (versus the lowest tertile) was associated with a 19% lower all-cause mortality risk (hazard ratio=0.81, 95% confidence interval: 0.70-0.92; P for trend=0.001) in women. Similarly, we observed inverse associations between milk intake and all-cause and cancer mortality risk in women, yogurt intake and cardiovascular disease risk in women, and yogurt intake and all-cause mortality risk in both sexes.

conclusionA higher total dairy and milk intakes in women and yogurt intake in both sexes were associated with a reduced risk of all-cause mortality in the general population across Japan during the 12-year follow-up period.

Indexed as

Cardiovascular DiseasesDairy ProductsNeoplasmsAdultAgedCause of DeathDietEast Asian PeopleFemaleFollow-Up StudiesHumansJapanLongitudinal StudiesMaleMiddle AgedRisk FactorsCohort studyDairy productsMilkMortalityYogurt

Identifiers

PMID39537182
PMCPMC12055505

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.