Evidence map›Paper›PMID 39537001›Full record

ArticleVascular pharmacology2024

Prolonged L-NAME exposure changes the vasodilator factor from NO to H

Natalya S Zinkevich, Kostiantyn Drachuk, David X Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vascular pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The role of NO, HBasic research in cardiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Natalya S ZinkevichCollege of Health, Science and Technology, School of Integrated Sciences, Sustainability, and Public Health, Biology, University of Illinois Springfield, Springfield, IL 62703-5407, USA; Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA; Department of Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA. Electronic address: nzink2@uis.edu.
Kostiantyn DrachukDepartment of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA; Department of Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA. Electronic address: kdrachuk@mcw.edu.
David X ZhangDepartment of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA; Department of Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA. Electronic address: xfzhang@mcw.edu.

Funding

TRP Channels In The Regulation of Vascular ToneR01HL096647 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI ZHANG, DAVID X. · 2011 to 2024
$5.5M
NHLBI NIH HHS R01 HL096647
6 · The paper itself

Abstract

The Ca

Indexed as

CalcimycinHydrogen PeroxideNG-Nitroarginine Methyl EsterNitric OxideVasodilationAgedArteriolesCatalaseCoronary Artery DiseaseEnzyme InhibitorsFemaleHumansMaleMiddle AgedNitric Oxide SynthaseVasodilator AgentsCalcimycinCatalaseEnzyme InhibitorsHydrogen PeroxideNG-Nitroarginine Methyl EsterNitric OxideNitric Oxide SynthaseVasodilator AgentsA23187Endothelium-dependent vasodilationMicrocirculationNitric oxideReactive oxygen species

Identifiers

PMID39537001
PMCPMC11624973

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.