ArticlePhysics in medicine and biology2024
Comparison of contrast-enhanced ultrasound imaging (CEUS) and super-resolution ultrasound (SRU) for the quantification of ischaemia flow redistribution: a theoretical study.
Article in Physics in medicine and biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Contrast-enhanced ultrasound for differentiating benign from malignant Breast Imaging Reporting and Data System 4a breast lesions: a prospective diagnostic accuracy study.Gland surgery · 2026Article
- Super-resolution contrast-enhanced ultrasound: recent advances.Ultrasonography (Seoul, Korea) · 2026Article
- Emerging Technologies for Exploring the Cellular Mechanisms in Vascular Diseases.International journal of molecular sciences · 2025Review
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7 authors.
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Abstract
The study of microcirculation can reveal important information related to pathology. Focusing on alterations that are represented by an obstruction of blood flow in microcirculatory regions may provide an insight into vascular biomarkers. The current in silico study assesses the capability of contrast enhanced ultrasound (CEUS) and super-resolution ultrasound imaging (SRU) flow-quantification to study occlusive actions in a microvascular bed, particularly the ability to characterise known and model induced flow behaviours. The aim is to investigate theoretical limits with the use of CEUS and SRU in order to propose realistic biomarker targets relevant for clinical diagnosis. Results from CEUS flow parameters display limitations congruent with prior investigations. Conventional resolution limits lead to signals dominated by large vessels, making discrimination of microvasculature specific signals difficult. Additionally, some occlusions lead to weakened parametric correlation against flow rate in the remainder of the network. Loss of correlation is dependent on the degree to which flow is redistributed, with comparatively minor redistribution correlating in accordance with ground truth measurements for change in mean transit time,dMTT(CEUS,
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