Evidence map›Paper›PMID 39536174›Full record

ArticleParasite (Paris, France)2024

Cryptosporidium spp. prevalence in the general population in Guinea: first large-scale screening study.

Timothé Guilavogui, Nausicaa Gantois, Jérémy Desramaut, Fode Ibrahima Cissé, Salif Cherif Touré, Bakary Luther Kourouma, Cristian Preda, Magali Chabé, Eric Viscogliosi, Gabriela Certad

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In one paragraph

Article in Parasite (Paris, France), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Timothé GuilavoguiCNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019-UMR 9017-CIIL-Centre d'Infection et d'Immunité de Lille, Université de Lille, 59000 Lille, France - Unité d'Appui à la Gestion et la Coordination des Programmes, Ministère de la Santé et de l'Hygiène Publique, Conakry BP 585, Guinea.
Nausicaa GantoisCNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019-UMR 9017-CIIL-Centre d'Infection et d'Immunité de Lille, Université de Lille, 59000 Lille, France.
Jérémy DesramautCNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019-UMR 9017-CIIL-Centre d'Infection et d'Immunité de Lille, Université de Lille, 59000 Lille, France.
Fode Ibrahima CisséHôpital National Ignace Deen CHU de Conakry, Laboratoire de Parasitologie, Conakry BP 1263, Guinea.
Salif Cherif TouréHôpital National Ignace Deen CHU de Conakry, Laboratoire de Parasitologie, Conakry BP 1263, Guinea.
Bakary Luther KouroumaCentre de Santé Anastasis, Conakry BP 1032, Guinea.
Cristian PredaDélégation à la Recherche Clinique et à l'Innovation, Groupement des Hôpitaux de l'Institut Catholique de Lille, Lille Catholic University, 59000 Lille, France.
Magali ChabéCNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019-UMR 9017-CIIL-Centre d'Infection et d'Immunité de Lille, Université de Lille, 59000 Lille, France.
Eric ViscogliosiCNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019-UMR 9017-CIIL-Centre d'Infection et d'Immunité de Lille, Université de Lille, 59000 Lille, France.
Gabriela CertadCNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019-UMR 9017-CIIL-Centre d'Infection et d'Immunité de Lille, Université de Lille, 59000 Lille, France - Délégation à la Recherche Clinique et à l'Innovation, Groupement des Hôpitaux de l'Institut Catholique de Lille, Lille Catholic University, 59000 Lille, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryptosporidium is a leading cause of diarrheal mortality in children in Africa and Asia. Despite the public health significance of this parasite, its molecular epidemiology and circulation in Guinea remain poorly understood. Therefore, this study aimed to determine the prevalence and genotype distribution of Cryptosporidium in the Guinean general population. To achieve this, fecal samples were collected from 834 individuals, both with and without digestive disorders, at two hospitals in Conakry. The presence of the parasite in the stool samples was detected using nested PCR targeting the SSU rDNA gene, followed by sequencing of the PCR products for genotyping of the isolates. The PCR-based prevalence was 0.12% for the whole cohort, and 0.2% among adults. The low frequency of Cryptosporidium observed in the current study is thus consistent with the prevalence of this parasite already reported in certain other African countries. The species identified in the positive samples was Cryptosporidium hominis. This study is the first to report the prevalence of Cryptosporidium in the general population of Guinea. Given the potential of this parasite to cause life-threatening diarrhea, further studies are needed to clarify the epidemiology of Cryptosporidium in this country.

Indexed as

CryptosporidiosisCryptosporidiumFecesGenotypePolymerase Chain ReactionAdolescentAdultAgedAged, 80 and overChildChild, PreschoolDiarrheaDNA, ProtozoanFemaleGuineaHumansDNA, ProtozoanAfricaCryptosporidium sppGuineaMolecular epidemiologyTransmissionZoonosis

Identifiers

PMID39536174
PMCPMC11560126

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.