Evidence map›Paper›PMID 39536115›Full record

ArticleScience advances2024

Experience-dependent, sexually dimorphic synaptic connectivity defined by sex-specific cadherin expression.

Chien-Po Liao, Maryam Majeed, Oliver Hobert

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Fertility reversibly modulatesbioRxiv : the preprint server for biology · 2026
    Article
  2. Review
  3. Nervous system-wide analysis of allScience advances · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Chien-Po LiaoDepartment of Biological Sciences, Columbia University, Howard Hughes Medical Institute, New York, NY 10027, USA.ORCID 0000-0002-7808-4211
Maryam MajeedDepartment of Biological Sciences, Columbia University, Howard Hughes Medical Institute, New York, NY 10027, USA.ORCID 0000-0003-4018-0766
Oliver HobertDepartment of Biological Sciences, Columbia University, Howard Hughes Medical Institute, New York, NY 10027, USA.ORCID 0000-0002-7634-2854

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
LIM HOMEOBOX GENE LIM-6 IN MOTOR NEURON DIFFERENTIATIONR01NS039996 · NINDS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Oliver Hobert · 2001 to 2026
$6.8M
Sexually dimorphic regulation of neuronal identity in C.elegansR37NS039996 · NINDS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI HOBERT, OLIVER · 2015 to 2021
$2.5M
NIH HHS P40 OD010440NINDS NIH HHS R01 NS039996NINDS NIH HHS R37 NS039996
6 · The paper itself

Abstract

Early-life experience influences subsequent maturation and function of the adult brain, sometimes even in a sex-specific manner, but underlying molecular mechanisms are poorly understood. We describe here how juvenile experience defines sexually dimorphic synaptic connectivity in the adult

Indexed as

CadherinsCaenorhabditis elegansCaenorhabditis elegans ProteinsSex CharacteristicsSynapsesAnimalsCyclic AMP Response Element-Binding ProteinFemaleInterneuronsMaleSerotoninTranscription FactorsCadherinsCaenorhabditis elegans ProteinsCyclic AMP Response Element-Binding ProteinSerotoninTranscription Factors

Identifiers

PMID39536115
PMCPMC11559607

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.