Evidence map›Paper›PMID 39535723›Full record

ArticleEuropean geriatric medicine2025

Healthcare costs in relation to kidney function among older people: the SCOPE study.

Francesco Balducci, Mirko Di Rosa, Regina Roller-Wirnsberger, Gerhard Wirnsberger, Francesco Mattace-Raso, Lisanne Tap, Francesc Formiga, Rafael Moreno-González, Tomasz Kostka, Agnieszka Guligowska and 9 more

Abstract readMulticenter Study
In one paragraph

Article in European geriatric medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Francesco BalducciCentre for Biostatistics and Applied Geriatric Clinical Epidemiology, Italian National Research Center on Aging (IRCCS INRCA), Ancona and Cosenza, Ancona, Italy.ORCID 0000-0001-9481-1274
Mirko Di RosaCentre for Biostatistics and Applied Geriatric Clinical Epidemiology, Italian National Research Center on Aging (IRCCS INRCA), Ancona and Cosenza, Ancona, Italy. m.dirosa@inrca.it.ORCID 0000-0002-1862-4159
Regina Roller-WirnsbergerDepartment of Internal Medicine, Medical University of Graz, Graz, Austria.ORCID 0000-0002-1273-6520
Gerhard WirnsbergerDepartment of Internal Medicine, Medical University of Graz, Graz, Austria.ORCID 0000-0001-7035-7038
Francesco Mattace-RasoSection of Geriatric Medicine, Department of Internal Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.ORCID 0000-0002-1688-6497
Lisanne TapSection of Geriatric Medicine, Department of Internal Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.ORCID 0000-0003-2989-4063
Francesc FormigaGeriatric Unit, Internal Medicine Department and Nephrology Department, Bellvitge University Hospital, IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.ORCID 0000-0002-3587-298X
Rafael Moreno-GonzálezGeriatric Unit, Internal Medicine Department and Nephrology Department, Bellvitge University Hospital, IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.ORCID 0000-0002-1535-064X
Tomasz KostkaDepartment of Geriatrics, Healthy Ageing Research Centre, Medical University of Lodz, Lodz, Poland.ORCID 0000-0003-0437-650X
Agnieszka GuligowskaDepartment of Geriatrics, Healthy Ageing Research Centre, Medical University of Lodz, Lodz, Poland.ORCID 0000-0002-6928-3892
Rada Artzi-MedvedikThe Recanati School for Community Health Professions at the Faculty of Health Sciences at Ben-Gurion University of the Negev, Beersheba, Israel.ORCID 0000-0003-0695-8845
Itshak MelzerThe Recanati School for Community Health Professions at the Faculty of Health Sciences at Ben-Gurion University of the Negev, Beersheba, Israel.ORCID 0000-0001-7769-845X
Christian WeingartDepartment of General Internal Medicine and Geriatrics, Krankenhaus Barmherzige Brüder Regensburg and Institute for Biomedicine of Aging, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Cornel SieberDepartment of General Internal Medicine and Geriatrics, Krankenhaus Barmherzige Brüder Regensburg and Institute for Biomedicine of Aging, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.ORCID 0000-0002-6271-7459
Johan ÄrnlövSchool of Health and Welfare, Dalarna University, Falun, Sweden.ORCID 0000-0002-6933-4637
Axel C CarlssonSchool of Health and Welfare, Dalarna University, Falun, Sweden.ORCID 0000-0001-6113-0472
Fabrizia LattanzioCentre for Biostatistics and Applied Geriatric Clinical Epidemiology, Italian National Research Center on Aging (IRCCS INRCA), Ancona and Cosenza, Ancona, Italy.ORCID 0000-0003-4051-1289
Andrea CorsonelloCentre for Biostatistics and Applied Geriatric Clinical Epidemiology, Italian National Research Center on Aging (IRCCS INRCA), Ancona and Cosenza, Ancona, Italy.ORCID 0000-0002-7276-3256
Screening for CKD among Older People across Europe (SCOPE) study investigators

Funding

Horizon 2020 () 634869
6 · The paper itself

Abstract

purposeIn this study, a comprehensive analysis of costs of chronic kidney disease (CKD) was performed, to understand factors associated with the economic burden of the disease in a multicentre international framework.

methodsThe impact on costs of demographics, socio-economics, clinical, and functional variables was tested in 2204 subjects aged 75 years or more attending outpatient clinics in Europe using a multicentre 2-year prospective cohort study. By means of collected resources consumption and unit cost data a comprehensive cost database was built and then investigated using multilevel regression modeling.

resultsOverall, hospitalization, medications and specialist visits were the main cost items, with a notable variability among countries. Estimated yearly costs were 4478€ ± 9804€, rising up to 6683€ ± 10,953€ for subjects with estimated Glomerular Filtration Rate (eGFR) < 30. Costs increased significantly according to the severity of the disease, gender and age. Clinical and functional covariates were also significantly associated with CKD-related total costs, even after correcting for the inter-country variability.

conclusionFindings corroborate the importance of multidimensional assessment of participants with CKD, as multimorbidity and functional disability produce a detrimental impact on participant's prognosis and cost of care. Preservation of functional impairment and adequate management of comorbidities may thus help decreasing the overall consumption on health care resources in CKD patients, especially in older people.

Indexed as

Health Care CostsRenal Insufficiency, ChronicAgedAged, 80 and overCost of IllnessEuropeFemaleGlomerular Filtration RateHospitalizationHumansMaleProspective StudiesChronic kidney diseaseHealthcare costsMulticentreOlder peopleResources consumption

Identifiers

PMID39535723
PMCPMC11850571

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.