ArticleMedical molecular morphology2025
Element analysis applied to investigate acute kidney injury induced by red yeast rice supplement.
Article in Medical molecular morphology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- One-Year Follow-Up of Red Yeast Rice-Associated Renal Dysfunction: A Report of Two Cases.Cureus · 2026Article
- Red yeast rice supplement containing silica nanoparticles induces renal injury in rats with unilateral nephrectomy.Clinical and experimental nephrology · 2026Article
- Elucidation of puberulic acid-induced nephrotoxicity using stem cell-based kidney organoids.Scientific reports · 2025Article
- Acute kidney injury due to inhalation of metal fumes.Clinical kidney journal · 2025Article
- A 28-day subacute toxicity study of puberulic acid in Crl:CD(SD) rats.Journal of toxicologic pathology · 2025Article
- Two Cases of Chronic Tubular Necrosis Presenting as Fanconi Syndrome Induced by Red Yeast Rice Choleste-Help.Diagnostics (Basel, Switzerland) · 2025Article
- Tubular damage and SGLT2 expression in a patient with Beni-koji tablet-associated acute kidney injury and Fanconi syndrome.CEN case reports · 2025Article
- Acute Tubular Injury and Fanconi Syndrome Associated With Red Yeast Rice Supplement.Kidney international reports · 2025Article
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Authors and funding
5 authors.
Funding
Abstract
Silica nanoparticles are used in functional foods and tablets to increase drug stability and delivery. We investigated a patient with acute kidney injury with Fanconi syndrome after taking functional food tablets made from red yeast rice using low-vacuum scanning electron microscopy (LVSEM) with an element analysis system. Kidney biopsy revealed proximal tubular necrosis and vacuolization with 10-20 nm black granules, which were similar to the silica nanoparticles found in the functional food tablets and urinary samples, as determined via LVSEM with element analysis. Reabsorbed silica nanoparticles induce oxidative stress in the kidney. Element analysis by LVSEM is useful to investigate a possible cause of acute tubular necrosis in patients with Fanconi syndrome.
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