Evidence map›Paper›PMID 39535548›Full record

ArticleEuropean journal of translational myology2024

Deceleration of denervated facial muscle atrophy through functional electrical stimulation: a sonographic quantification in patients with facial nerve paralysis.

Gabriel Meincke, Johannes Krauß, Maren Geitner, Anna-Maria Kuttenreich, Dirk Arnold, Jonas Ballmaier, Thomas Lehmann, Winfried Mayr, Orlando Guntinas-Lichius, Gerd Fabian Volk

Abstract read
In one paragraph

Article in European journal of translational myology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gabriel MeinckeENT-Department, Jena University Hospital, Jena. gabriel.meincke@uni-jena.de.
Johannes KraußENT-Department, Jena University Hospital, Jena. johannes.krauss@uni-jena.de.
Maren GeitnerENT-Department, Jena University Hospital, Jena, Germany; Facial-Nerve-Center, Jena University Hospital, Jena. maren.geitner@med.uni-jena.de.
Anna-Maria KuttenreichENT-Department, Jena University Hospital, Jena, Germany; Facial-Nerve-Center, Jena University Hospital, Jena. anna.kuttenreich@rwth-aachen.de.
Dirk ArnoldENT-Department, Jena University Hospital, Jena, Germany; Facial-Nerve-Center, Jena University Hospital, Jena. dirk.arnold@med.uni-jena.de.
Jonas BallmaierENT-Department, Jena University Hospital, Jena, Germany; Facial-Nerve-Center, Jena University Hospital, Jena. jonas.ballmaier@med.uni-jena.de.
Thomas LehmannInstitute for Medical Statistics, Computer Science and Data Science, Jena University Hospital, Jena. thomas.lehmann@med.uni-jena.de.
Winfried MayrCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna. winfried.mayr@meduniwien.ac.at.
Orlando Guntinas-LichiusENT-Department, Jena University Hospital, Jena, Germany; Facial-Nerve-Center, Jena University Hospital, Jena, Germany; Center of Rare Diseases, Jena University Hospital, Jena. orlando.guntinas@med.uni-jena.de.
Gerd Fabian VolkENT-Department, Jena University Hospital, Jena, Germany; Facial-Nerve-Center, Jena University Hospital, Jena, Germany; Center of Rare Diseases, Jena University Hospital, Jena. fabian.volk@med.uni-jena.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Functional Electrical Stimulation (FES) is an established intervention for a range of muscular and neurological disorders that has already been studied in numerous publications. However, its application to Peripheral Facial nerve Paralysis (PFP) still needs to be sufficiently investigated. As the first approach known to the authors, this study examines the effect of FES on the facial muscles in complete PFP using ultrasonography as a means of observation. In a prospective single-center observational pilot study, ten patients with complete PFP, confirmed by needle-electromyography (EMG), performed FES of the affected lateral mouth region at home twice daily for 20 minutes. The facial muscles' Cross-Sectional Area (CSA) was regularly assessed using sonographic quantification. While the CSA of most non-stimulated muscles decreased considerably during ongoing paralysis, a significant CSA increase of the Zygomaticus Muscle (ZYG), which was regularly subjected to FES, could be demonstrated. FES can halt the atrophy of denervated ZYG and potentially other facial muscles. Further investigations with a more significant patient collective are recommended. From now on, FES could be established as an additive method in the non-invasive treatment of PFP.

Identifiers

PMID39535548
PMCPMC11726303

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.