Evidence map›Paper›PMID 39535494›Full record

ArticleMicrobiologyOpen2024

The Effects of Carbonate on Candida albicans Filamentation, Biofilm Formation, and Antifungal Resistance.

Trenton P Miedema, Kayla E Grooters, Ian A Cleary

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MicrobiologyOpen, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Trenton P MiedemaDepartment of Biomedical Sciences, Grand Valley State University, Allendale, Michigan, USA.
Kayla E GrootersDepartment of Biomedical Sciences, Grand Valley State University, Allendale, Michigan, USA.
Ian A ClearyDepartment of Biomedical Sciences, Grand Valley State University, Allendale, Michigan, USA.ORCID 0000-0002-3958-431X

Funding

This work was supported in part by the Office of Undergraduate Research and Scholarship at GVSU and a Kindschi Undergraduate Research Fellowship in the Sciences to TPM.
6 · The paper itself

Abstract

Candida albicans, a member of the normal microbial population of healthy humans, is an opportunistic pathogen that can cause serious disease in immunocompromised patients. An important virulence factor of C. albicans is the formation of biofilms. These organized communities of cells are efficient at attaching to host cells and implanted medical devices. Carbonate has been studied as an agricultural antifungal agent, and here we demonstrate that carbonate can affect filamentation, biofilm formation, and antifungal drug resistance in C. albicans.

Indexed as

Antifungal AgentsBiofilmsCandida albicansCarbonatesDrug Resistance, FungalHumansHyphaeMicrobial Sensitivity TestsAntifungal AgentsCarbonatesantifungalsCandida albicanscarbonatefilamentation

Identifiers

PMID39535494
PMCPMC11558181

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.