Evidence map›Paper›PMID 39535372›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Inactivation of Pseudovirus Expressing the D614G Spike Protein Mutation using Nitric Oxide-Plasma Activated Water.

Paritosh Patel, Neha Kaushik, Tirtha Raj Acharya, Sudakshya S Lenka, Soujanya Ghosh, Rizwan Wahab, Suresh K Verma, Eun Ha Choi, Nagendra Kumar Kaushik

Abstract read
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In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Paritosh PatelDepartment of Electrical and Biological Physics, Plasma Bioscience Research Center, Kwangwoon University, Seoul, 01897, South Korea.
Neha KaushikDepartment of Biotechnology, College of Engineering, The University of Suwon, Hwaseong, 18323, South Korea.
Tirtha Raj AcharyaDepartment of Electrical and Biological Physics, Plasma Bioscience Research Center, Kwangwoon University, Seoul, 01897, South Korea.
Sudakshya S LenkaSchool of Biotechnology, KIIT University, Bhubaneswar, Odisha, 751024, India.
Soujanya GhoshSchool of Biotechnology, KIIT University, Bhubaneswar, Odisha, 751024, India.
Rizwan WahabDepartment of Zoology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.
Suresh K VermaSchool of Biotechnology, KIIT University, Bhubaneswar, Odisha, 751024, India.
Eun Ha ChoiDepartment of Electrical and Biological Physics, Plasma Bioscience Research Center, Kwangwoon University, Seoul, 01897, South Korea.
Nagendra Kumar KaushikDepartment of Electrical and Biological Physics, Plasma Bioscience Research Center, Kwangwoon University, Seoul, 01897, South Korea.ORCID 0000-0002-4965-5046

Funding

King Saud University: Researchers Supporting Project Number RSPD2024R1042Kwangwoon UniversityNational Research Foundation of Korea 2021R1A6A1A03038785
6 · The paper itself

Abstract

Variants of concern (VOCs) of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) exhibit high infectivity due to mutations, particularly in the spike protein, that facilitate enhanced binding of virus to human angiotensin-converting enzyme 2 (hACE2). The D614G mutation, situated in S1-domain, promotes the open conformation of spike protein, augmenting its interaction with hACE2. Activated water neutralizes pathogens by damaging biological molecules; however, its effect on mutated SARS-CoV-2 or VOCs requires further exploration. Here, the efficacy of nitric oxide (NO

Indexed as

MutationNitric OxideSARS-CoV-2Spike Glycoprotein, CoronavirusAnimalsCOVID-19HumansVirus InactivationWaterNitric OxideSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2Watermutated virus inactivationnitric oxidesplasma activated waterSARS‐CoV‐2 pseudovirus D614G spike mutantvariants of concern

Identifiers

PMID39535372
PMCPMC11672301

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.