Evidence map›Paper›PMID 39535328›Full record

ArticleJournal of clinical pharmacology2025

Training the Next Generation of Pediatric Clinical Pharmacologists: Insights and Trainee Perspectives Over 10 Years.

Rachel L Randell, Rose Gelineau-Morel, Sydney Thomas, Daniel Gonzalez, J Steven Leeder, Christoph P Hornik

Abstract read
In one paragraph

Article in Journal of clinical pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rachel L RandellDepartment of Pediatrics, Department of Medicine, Duke University, Durham, North Carolina, USA.
Rose Gelineau-MorelChildren's Mercy Kansas City and University of Missouri-Kansas City School of Medicine, Kansas City, Missouri, USA.ORCID 0000-0002-7387-9082
Sydney ThomasOmeta Labs, San Diego, California, USA.
Daniel GonzalezDepartment of Pediatrics, Department of Medicine, Duke University, Durham, North Carolina, USA.
J Steven LeederChildren's Mercy Kansas City and University of Missouri-Kansas City School of Medicine, Kansas City, Missouri, USA.
Christoph P HornikDepartment of Pediatrics, Department of Medicine, Duke University, Durham, North Carolina, USA.

Funding

The impact of ampicillin and breast milk oligosaccharides on the infant microbiome and immune functionsP50HD106463 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ADRIANA H TREMOULET · 2021 to 2026
$19.6M
UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program-Evaluation SupplementT32GM086330 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KIM L.R. BROUWER, Daniel Gonzalez · 2011 to 2026
$8.5M
Application of Physiologically-Based Pharmacokinetic Modeling to Characterize Drug-Drug Interactions in InfantsR01HD102949 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Daniel Gonzalez · 2021 to 2026
$3.0M
PRISMR01HD113201 · NICHD · DUKE UNIVERSITY · PI Daniel Gonzalez, Jason E. Lang · 2023 to 2026
$2.7M
Physiologically-Based Pharmacokinetic Modeling to Guide Drug Dosing in Children with ObesityR01HD096435 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DUMOND, JULIE BRUMER · 2018 to 2022
$2.0M
Developing Pediatric Clinical Pharmacologists for the Advancement of TherapeuticsT32HD087978 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NIZET, VICTOR, TREMOULET, ADRIANA H · 2016 to 2025
$1.5M
National Career Development Program for Researchers in Pediatric Clinical PharmacologyK12HD113189 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DANIEL K. BENJAMIN, Daniel Gonzalez · 2023 to 2026
$1.2M
Duke-UNC Collaborative Pediatric Clinical Pharmacology Postdoctoral Training ProgramT32HD104576 · NICHD · DUKE UNIVERSITY · PI BROUWER, KIM L.R., GONZALEZ, DANIEL · 2021 to 2025
$962k
National Institute of Child Health and Human Development 7K12HD113189National Institute of Child Health and Human Development P50HD106463National Institute of Child Health and Human Development T32HD087978National Institute of Child Health and Human Development T32HD104576NICHD NIH HHS HHSN275201000003CNICHD NIH HHS HHSN275201000003INICHD NIH HHS K12 HD113189NICHD NIH HHS P50 HD106463NICHD NIH HHS R01 HD096435NICHD NIH HHS R01 HD102949NICHD NIH HHS R01 HD113201NICHD NIH HHS T32 HD087978NICHD NIH HHS T32 HD104576NIGMS NIH HHS T32 GM086330
6 · The paper itself

Abstract

The limited number of researchers with expertise necessary toaddress treatment gaps for children presents an ongoing challenge. The NationalInstitutes of Health established a national Pediatric Clinical Pharmacology T32Training Program in 2012 to train a multidisciplinary, collaborative pediatricclinical pharmacology workforce. We surveyed all current T32 trainees andgraduates since inception to identify strengths and opportunities to enhanceworkforce development. A total of 85 out of 155 (55%) responded, with themajority of respondents being female gender (61%), white race (75%), andworking in academia (75%). Nearly all (97%) reported using clinicalpharmacology in their current position, with 88% planning to remain in clinicalpharmacology in the long term, reinforcing current training efforts. Lifestylefactors and student debt appeared to influence career decisions. Mentors werecritical for introduction and future success in the field. Time and fundinglimitations were perceived as barriers to successful training. There was also apressing need to improve diversity. For workforce development, we suggestsupporting: (1) trainees' lifestyle, by offsetting financial pressures ofresearch training and expanding the geographic footprint of pediatric clinicalpharmacology training; (2) mentorship, by identifying mentors in the field andproviding dedicated support for mentorship; (3) efficiency, by evaluatingcurrent training activities and focusing on activities that maximizeopportunities for future funding; and (4) diversity, by examining barriers todiversity in the workforce in general and expanding early enrichmentopportunities.

Indexed as

PediatricsPharmacology, ClinicalChildFemaleHumansMaleMentorsSurveys and Questionnairesclinical pharmacologyeducationpediatricsspecial populationstraining

Identifiers

PMID39535328
PMCPMC12051475

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.