Evidence map›Paper›PMID 39535218›Full record

ArticlemBio2024

Role of VapBC4 toxin-antitoxin system of

Arghya Bhowmick, Alejandra Recalde, Chandrima Bhattacharyya, Ankita Banerjee, Jagriti Das, Ulises E Rodriguez-Cruz, Sonja-Verena Albers, Abhrajyoti Ghosh

Abstract read
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Arghya BhowmickDepartment of Biological Sciences, Bose Institute, Kolkata, India.
Alejandra RecaldeMolecular Biology of Archaea, Microbiology, Faculty of Biology, University of Freiburg, Freiburg, Germany.
Chandrima BhattacharyyaDepartment of Biological Sciences, Bose Institute, Kolkata, India.
Ankita BanerjeeDepartment of Biological Sciences, Bose Institute, Kolkata, India.
Jagriti DasDepartment of Biological Sciences, Bose Institute, Kolkata, India.
Ulises E Rodriguez-CruzDepartment of Evolutionary Ecology, Institute of Ecology, National Autonomous University of Mexico, Mexico City, Mexico.
Sonja-Verena AlbersMolecular Biology of Archaea, Microbiology, Faculty of Biology, University of Freiburg, Freiburg, Germany.ORCID 0000-0003-2459-2226
Abhrajyoti GhoshDepartment of Biological Sciences, Bose Institute, Kolkata, India.ORCID 0000-0002-2469-3740

Funding

Bose Institute Intramural FundCouncil of Scientific and Industrial Research, India (CSIR) 09/015(0525)/2017-EMR-IEuropean Molecular Biology Organization (EMBO) SEG 9915Volkswagen Foundation (VolkswagenStiftung) AZ96727
6 · The paper itself

Abstract

Toxin-antitoxin (TA) systems are important for stress adaptation in prokaryotes, including persistence, antibiotic resistance, pathogenicity, and biofilm formation. Toxins can cause cell death, reversible growth stasis, and direct inhibition of crucial cellular processes through various mechanisms, while antitoxins neutralize the effects of toxins. In bacteria, these systems have been studied in detail, whereas their function in archaea remains elusive. During heat stress, the thermoacidophilic archaeon IMPORTANCE: This research enhances our knowledge of toxin-antitoxin (TA) systems in archaea, specifically in the thermoacidophilic archaeon

Indexed as

Sulfolobus acidocaldariusToxin-Antitoxin SystemsAntitoxinsArchaeal ProteinsGene Expression Regulation, ArchaealHeat-Shock ResponseHot TemperatureAntitoxinsArchaeal Proteinsarchaeabiofilmsheat-stresspersistersSulfolobus acidocaldariusToxin-antitoxin

Identifiers

PMID39535218
PMCPMC11633383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.