ArticleJournal of clinical research in pediatric endocrinology2025
Normative Values for Thyroid Volume and Tracheal Index in Healthy Turkish Newborns in an Iodine Sufficient Region
Article in Journal of clinical research in pediatric endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07579988 (Ultrasound Measurement of Thyroid Volume in Term Newborns), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ultrasound Measurement of Thyroid Volume in Term Newborns : a Single-centre Cross Sectional Observational Study
Who cites it
1 citing paper in PubMed.
- A novel homozygous thyroglobulin gene variant presenting with massive congenital goiter and neonatal airway obstruction.Hormones (Athens, Greece) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aimed to determine the normal values of thyroid volume and tracheal index in healthy, term newborns born in an iodine-sufficient population. Moreover, the usability of a handheld device for assessing tracheal index was assessed. Methods: Thyroid imaging was performed at 0-2 days and 15-30 days using handheld and portable ultrasound (US) devices. Thyroid volume and tracheal index were calculated using standard formulae. Results: A total of 144 healthy, term newborns with a mean birth weight 3230 g were enrolled. The normal thyroid volume for the entire population was 0.66±0.25 mL at 0-2 days, which significantly increased to 1.12±0.33 mL at 15-30 days (p<0.01). There were no significant differences in thyroid volume between genders in either age group (p=0.246 and p=0.879). Thyroid volume correlated with birth weight, length, and head circumference, with the strongest correlation being with birth weight (r=0.404, p<0.001; r=0.252, p=0.002; r=0.223, p=0.007, respectively). The tracheal index at 0-2 days was 1.84±0.30 in girls, 1.82±0.27 in boys, and 1.83±0.29 overall. At 15-30 days, it was 1.99±0.23 in girls, 2.00±0.28 in boys, and 1.99±0.25 overall. Similar to thyroid volume, the tracheal index increased significantly with age (p<0.01), with no significant gender differences in either age group (p=0.593 and p=0.886). Thyroid volume and tracheal index were moderately correlated in both measurements (rho=0.538, p<0.01). Measurements of the trachea, and thyroid lobe widths using portable and handheld US devices were positively correlated (r=0.449, p<0.01; r=0.638, p<0.01; r=0.497, p<0.01). There was also a correlation between tracheal index measurements using both devices at both the first and second measurements. Conclusion: This study provides normative data for thyroid volumes and tracheal index in newborns from an iodine-sufficient population. The tracheal index may be used to estimate thyroid size when volume calculation is not feasible. Handheld US devices are effective for this assessment.
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