Evidence map›Paper›PMID 39535088›Full record

Observational studyCardiology journal2025

A real-life clinical application of cardiac magnetic resonance imaging in patients with acute myocarditis - one-center observational retrospective study.

Bartosz Gruchlik, Agnieszka Nowotarska, Sylwia Ścibisz-Brenkus, Martyna Nowak, Wiktor Werenkowicz, Małgorzata Niemiec, Andrzej Swinarew, Barbara Mika, Wojciech Wróbel, Maciej Haberka and 2 more

Abstract readObservational Study
In one paragraph

Observational study in Cardiology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Bartosz GruchlikFirst Department of Cardiology, Medical University of Silesia, Katowice, Poland.
Agnieszka NowotarskaFirst Department of Cardiology, Medical University of Silesia, Katowice, Poland.
Sylwia Ścibisz-BrenkusFirst Department of Cardiology, Medical University of Silesia, Katowice, Poland.
Martyna NowakFirst Department of Cardiology, Medical University of Silesia, Katowice, Poland.
Wiktor WerenkowiczFirst Department of Cardiology, Medical University of Silesia, Katowice, Poland.
Małgorzata NiemiecFirst Department of Cardiology, Medical University of Silesia, Katowice, Poland.
Andrzej SwinarewFaculty of Science and Technology, University of Silesia in Katowice, Chorzow, Poland.
Barbara MikaFaculty of Science and Technology, University of Silesia in Katowice, Chorzow, Poland.
Wojciech WróbelFirst Department of Cardiology, Medical University of Silesia, Katowice, Poland.
Maciej HaberkaSecond Department of Cardiology, Medical University of Silesia, Katowice, Poland.
Bartłomiej StasiówThe Unit of Diagnostic Imaging, Medical University of Silesia, Katowice, Poland.
Katarzyna Mizia-StecFirst Department of Cardiology, Medical University of Silesia, Katowice, Poland. kmiziastec@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe diagnosis of acute myocarditis is complex, with cardiac magnetic resonance (CMR) being a recommended diagnostic method. This study aimed to evaluate the real-life use of CMR in the diagnosis of acute myocarditis and to correlate CMR results with the degree of myocardial damage.

methodsThis is a retrospective, observational tertiary single-center study of 90 consecutive patients (F/M:18/72, mean age:39 ± 14 years) hospitalized between 2015-2022 with a clinical diagnosis of acute myocarditis. The study population was divided into two groups: patients who underwent CMR+ and those who did not undergo CMR - In the CMR+ group, various sequences, including T1/T2-weighted imaging, late gadolinium enhancement (LGE), and mapping techniques, were used to assess myocardial inflammation and damage.

resultsCMR was performed in 39 patients (43.3%, F/M:10/29, mean age:41 ± 16 years). In this group, myocardial edema (increased T2 signal intensity) was detected in 29 patients, and LGE (signal intensity 2 standard deviations cabove normal on T1 images) was found in 39 patients. Diagnosis based on Lake Louise Criteria was possible in 29 cases. Edema negatively correlated with TnT levels (r = -0.412, p < 0.05) and positively with the number of LGE segments (r = 0.372, p < 0.05). Significant correlations were found between LVEF and LGE mass (r = -0.360, p < 0.05), and maximal TnT levels (r = -0.38, p < 0.05). CMR+ patients had lower myocardial damage markers and CRP concentrations compared to CMR- patients.

conclusionsCMR is underused in diagnosing acute myocarditis. Myocardial damage markers correlate with CMR-detected edema and volumetric measures, but not LGE extent. More research is needed to enhance risk assessment and treatment.

Indexed as

Magnetic Resonance Imaging, CineMyocarditisMyocardiumAcute DiseaseAdultFemaleHumansMaleMiddle AgedPredictive Value of TestsRetrospective Studiesacute myocarditiscardiac magnetic resonanceLake Louise Criterialate gadolinium enhancementregion of interest mass

Identifiers

PMID39535088
PMCPMC11870014

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.