ReviewCureus2024
Unraveling the Impact of Travel on Circadian Rhythm and Crafting Optimal Management Approaches: A Systematic Review.
Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Circadian rhythms, which regulate essential physiological and behavioral processes, are crucial for maintaining overall health and well-being. However, disruptions to these rhythms, particularly due to trans-meridian travel and shift work, can lead to significant health issues, including jet lag, metabolic imbalances, and neuropsychiatric disorders. In this systematic review, conducted in line with Preferred Reporting Items for Systematic Reviews and Metanalysis (PRISMA) 2020 guidelines, we explore the effectiveness of various interventions aimed at realigning circadian rhythms disrupted by such factors. Focusing on studies published between 2020 and 2024, our search spanned databases like PubMed, Google Scholar, PubMed Central (PMC), and ScienceDirect, emphasizing randomized controlled trials (RCTs), observational studies, and comprehensive reviews. A rigorous quality assessment using the AMSTAR tool for systematic reviews and the SANRA checklist for narrative reviews was employed. Out of an initial 2153 titles, 23 high-quality studies were identified and analyzed. The findings reveal that interventions such as melatonin supplementation, personalized light exposure, and chrono-modulation can significantly improve sleep quality, reduce jet lag symptoms, and promote better health outcomes. This review highlights the critical nature of circadian alignment in preventing serious health issues, such as mental health disorders, metabolic syndromes, and even cancer. It advocates for a personalized, integrative approach that combines melatonin, light therapy, time-restricted eating, exercise, and alternative therapies like electroacupuncture. Such strategies not only facilitate smoother transitions across time zones but also contribute to overall health and resilience. Future studies should aim to assess the long-term benefits and practical applications of these interventions in broader populations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.