Evidence map›Paper›PMID 39534804›Full record

ArticleCureus2024

Comparing the Postoperative Analgesic Efficacy of Ketorolac and Tramadol After Open Inguinal Hernia Mesh Repair: A Randomized Controlled Trial.

Syed M Ahmed, Sidra Shabbir, Nauman A Rana, Atia Khatoon, Umar F Ghani, Irmaghana Basharat, Muhammad N Khan, Fahd M Hameed, Muhammad F Dar

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Syed M AhmedGeneral Surgery, Pakistan Air Force Hospital, Islamabad, PAK.
Sidra ShabbirGeneral Surgery, Pakistan Air Force Hospital, Islamabad, PAK.
Nauman A RanaGeneral Surgery, Pakistan Air Force Hospital, Islamabad, PAK.
Atia KhatoonGeneral Surgery, Pakistan Air Force Hospital, Islamabad, PAK.
Umar F GhaniGeneral Surgery, Pakistan Air Force Hospital, Islamabad, PAK.
Irmaghana BasharatGeneral Surgery, Pakistan Air Force Hospital, Islamabad, PAK.
Muhammad N KhanGeneral Surgery, Pakistan Air Force Hospital, Islamabad, PAK.
Fahd M HameedGeneral Surgery, Pakistan Air Force Hospital, Islamabad, PAK.
Muhammad F DarGeneral Surgery, Pakistan Air Force Hospital, Islamabad, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Opioids are the mainstay for postoperative pain control. However, due to the increasing dependence on opioids and their side effects, multiple adjuncts are used to reduce opioid consumption, including non-steroidal anti-inflammatory drugs (NSAIDs). Inguinal hernia repair is one of the most common procedures performed by general surgeons worldwide. Despite various advancements in operative techniques, postoperative pain remains a major risk factor for morbidity and delayed hospital discharge following surgery. Objective The objective of this study was to compare ketorolac with tramadol for postoperative pain control following open inguinal hernia mesh repair. Methods This was a randomized controlled trial. Sixty patients undergoing unilateral primary open inguinal hernia repair with mesh were randomly divided into two groups: Group A received injection ketorolac intravenously postoperatively, while Group B received injection tramadol intravenously following surgery. Pain scores and vitals were measured at two, six, 12, and 24 hours post procedure. Other secondary outcomes included the time for nausea to stop, time to pass flatus, and time to start ambulation. Data was analyzed by independent-sample t-test using IBM SPSS Statistics for Windows, Version 30.0 (Release 2024; IBM Corp., Armonk, New York, United States); a p-value of < 0.05 was considered significant. Results Pain scores were lower in the ketorolac group when compared to tramadol. However, patients in the tramadol group had nausea for a longer duration, delayed return of bowel function, and took longer to start ambulation. There was no significant difference in vitals. Conclusion Injection ketorolac, when used in isolation, provides more effective postoperative analgesia along with fewer side effects when compared to tramadol in inguinal hernia repair.

Indexed as

inguinal hernia repairketorolac tromethaminelichtenstein’s repairtramadol hclvisual analog scale

Identifiers

PMID39534804
PMCPMC11556412

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.