ArticleMalaysian family physician : the official journal of the Academy of Family Physicians of Malaysia2024
Association between medication adherence and blood pressure control and factors associated with antihypertensive medication adherence in the Melaka Tengah District: A cross-sectional survey.
Article in Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed.
- Structural analysis of causal pathways between adherence, satisfaction and clinical outcomes in hypertensive patients using a mobile adherence intervention: A SEM-NCA-cIPMA approach.Journal of human hypertension · 2026Trial
- Mapping Pharmacogenomic Determinants of Adverse Drug Reactions in Hypertension: A Systematic Review.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Prevalence and factors associated with controlled blood pressure among hypertensive patients in a Malaysian primary health clinic-a cross-sectional study.BMC primary care · 2026Article
- Impact of Antihypertensive Treatment Adherence on Premature Mortality over Seven Years: A Follow-Up Investigation.Journal of clinical medicine · 2025Article
- Clinical Implementation of the Hill-Bone Compliance to High Blood Pressure Therapy Scale: Antihypertensive Adherence Assessment in a Romanian Cardiology Outpatient Center.Patient preference and adherence · 2025Article
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Abstract
Introduction: The burden of cardiovascular disease and early morbidity and mortality is exacerbated by hypertension. According to the 2019 National Health and Morbidity Survey, 30% of adults in Malaysia aged over 18 years had hypertension. Our study aimed to investigate the association between medication adherence and blood pressure control and the factors associated with antihypertensive medication adherence. Methods: This cross-sectional study was conducted among adult patients with hypertension who had been under treatment at public primary health clinics in the Melaka Tengah District. A self-administered questionnaire was used, and blood pressure was measured. Descriptive and multivariate logistic regression analyses were conducted using the Statistical Package for the Social Sciences (version 28). Results: A total of 1531 patients were recruited in this study. Among them, 74.1% had good antihypertensive medication adherence, and 51.4% had their blood pressure controlled. Medication adherence was significantly associated with blood pressure control (P<0.005). The multivariate analysis showed that the determinants for antihypertensive medication non-adherence were Malay ethnicity, secondary education, farther distance from the clinic, experience of side effects of antihypertensive medications, concern about long-term side effects and usage of alternative medicine (P<0.05). Taking multiple antihypertensive medications was the only factor associated with uncontrolled blood pressure (P<0.05). Conclusion: Addressing issues on medication adherence is important to ensure blood pressure control. The factors associated with non-adherence should be closely monitored to improve blood pressure control and prevent adverse health outcomes. Single-pill combination antihypertensive medications are encouraged to reduce pill burden and improve blood pressure control.
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