Evidence map›Paper›PMID 39534680›Full record

ArticleMaterials today. Bio2024

An intelligent poly aptamer-encoded DNA nanoclew for tumor site activated mitochondria-targeted photodynamic therapy and MR imaging.

Minghui Chen, Hanbo Xu, Pengzhao Chang, Xueqi Li, Shuang Liu, Lingyue Xu, Kai Xu, Guohui Cheng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Polymeric nanocarriers for subcellular targeting in photodynamic therapy.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Minghui ChenSchool of Medical Imaging, Xuzhou Medical University, Xuzhou, 221004, PR China.
Hanbo XuSchool of Medical Imaging, Xuzhou Medical University, Xuzhou, 221004, PR China.
Pengzhao ChangSchool of Medical Imaging, Xuzhou Medical University, Xuzhou, 221004, PR China.
Xueqi LiSchool of Medical Imaging, Xuzhou Medical University, Xuzhou, 221004, PR China.
Shuang LiuSchool of Pharmacy, Xuzhou Medical University, Xuzhou, 221004, PR China.
Lingyue XuSchool of Medical Imaging, Xuzhou Medical University, Xuzhou, 221004, PR China.
Kai XuSchool of Medical Imaging, Xuzhou Medical University, Xuzhou, 221004, PR China.
Guohui ChengSchool of Pharmacy, Xuzhou Medical University, Xuzhou, 221004, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondria-targeted photodynamic therapy (PDT) has emerged as one of the most promising antitumor therapies, as it significantly enhances the efficacy of photosensitizers. An efficient and biocompatible nanocarrier to deliver cationic photosensitizers (PSs) is vital for mitochondria-targeted PDT but still challenging. Herein, a poly-AS1411 aptamer DNA nanoclew (AS-AMD) synthesized via rolling circle amplification (RCA) is developed, incorporating mitochondria-targeted PSs (APNO) and paramagnetic Mn

Indexed as

AS1411DNA nanostructureMitochondria-targeted PDTMR imagingNanotheranostic agents

Identifiers

PMID39534680
PMCPMC11554627

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.